ChemicalBook > CAS DataBase List > 2-amino-6-methoxybenzonitrile

2-amino-6-methoxybenzonitrile

Product Name
2-amino-6-methoxybenzonitrile
CAS No.
1591-37-3
Chemical Name
2-amino-6-methoxybenzonitrile
Synonyms
2-AMino-6-Methoxy-benzonitril;2-amino-6-methoxybenzonitrile;Benzonitrile, 2-amino-6-methoxy-
CBNumber
CB01557600
Molecular Formula
C8H8N2O
Formula Weight
148.16
MOL File
1591-37-3.mol
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2-amino-6-methoxybenzonitrile Property

Melting point:
141 °C
Boiling point:
339.4±27.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
1.39±0.10(Predicted)
Appearance
Light brown to brown Solid
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A898193
Product name
2-Amino-6-methoxybenzonitrile
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-618
Product name
2-Amino-6-methoxybenzonitrile
Packaging
1g
Price
$72
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA10519
Product name
2-Amino-6-methoxybenzonitrile
Packaging
1g
Price
$100
Updated
2021/12/16
AK Scientific
Product number
Z4229
Product name
2-Amino-6-methoxybenzonitrile
Packaging
1g
Price
$131
Updated
2021/12/16
Matrix Scientific
Product number
126220
Product name
2-Amino-6-methoxybenzonitrile
Purity
>95%
Packaging
1g
Price
$180
Updated
2021/12/16
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2-amino-6-methoxybenzonitrile Chemical Properties,Usage,Production

Synthesis

77326-36-4

124-41-4

1591-37-3

Sodium methanolate (25% w/w in MeOH, 325 μL, 1.42 mmol, 1.1 eq.) was added to a solution of 2-amino-6-fluorobenzonitrile (176 mg, 1.29 mmol, 1.0 eq.) dissolved in DMF (1.00 mL) at room temperature, and the reaction was stirred for 18 hours. Upon completion of the reaction, the reaction solution was concentrated in vacuum and the residue was mixed with deionized water (10 mL) and stirred to precipitate a beige colored precipitate. The precipitate was collected by filtration under reduced pressure, dissolved in ethyl acetate and then concentrated again, ground with hexane, and finally the residual solvent was removed in vacuum to give 2-amino-6-methoxybenzonitrile (158 mg, 1.07 mmol, 83% yield) as a beige amorphous solid; melting point 143-145°C, literature value 136-140°C.

References

[1] Synthesis (Germany), 2017, vol. 49, # 1, p. 135 - 144
[2] Patent: WO2005/35486, 2005, A1. Location in patent: Page/Page column 49
[3] Patent: WO2006/56433, 2006, A2. Location in patent: Page/Page column 31-32

2-amino-6-methoxybenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-amino-6-methoxybenzonitrile manufacturers

Career Henan Chemical Co
Product
2-amino-6-methoxybenzonitrile 1591-37-3
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500kg
Release date
2018-08-19

1591-37-3, 2-amino-6-methoxybenzonitrileRelated Search:


  • 2-amino-6-methoxybenzonitrile
  • 2-AMino-6-Methoxy-benzonitril
  • Benzonitrile, 2-amino-6-methoxy-
  • 1591-37-3