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4-bromo-2-(bromomethyl)-1-nitrobenzene

Product Name
4-bromo-2-(bromomethyl)-1-nitrobenzene
CAS No.
35287-42-4
Chemical Name
4-bromo-2-(bromomethyl)-1-nitrobenzene
Synonyms
5-bromo-2-nitrobenzyl bromide;L-Valine,5-mercapto-,methylester;4-bromo-2-(bromomethyl)-1-nitrobenzene;Benzene, 4-bromo-2-(bromomethyl)-1-nitro-
CBNumber
CB01559376
Molecular Formula
C7H5Br2NO2
Formula Weight
294.93
MOL File
35287-42-4.mol
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4-bromo-2-(bromomethyl)-1-nitrobenzene Property

Boiling point:
330.2±27.0 °C(Predicted)
Density 
2.006±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
crystalline solid
color 
Light yellow
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Safety

HS Code 
2904990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR400606
Product name
5-Bromo-2-nitrobenzylbromide
Packaging
250mg
Price
$114
Updated
2021/12/16
SynQuest Laboratories
Product number
4754-9-45
Product name
5-Bromo-2-nitrobenzyl bromide
Packaging
250mg
Price
$125
Updated
2021/12/16
Apolloscientific
Product number
OR400606
Product name
5-Bromo-2-nitrobenzylbromide
Packaging
1g
Price
$279
Updated
2021/12/16
SynQuest Laboratories
Product number
4754-9-45
Product name
5-Bromo-2-nitrobenzyl bromide
Packaging
1g
Price
$308
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0047104
Product name
4-BROMO-2-(BROMOMETHYL)-1-NITROBENZENE
Purity
95.00%
Packaging
5MG
Price
$505.65
Updated
2021/12/16
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4-bromo-2-(bromomethyl)-1-nitrobenzene Chemical Properties,Usage,Production

Synthesis

1241894-37-0

35287-42-4

To a stirred solution of (5-bromo-2-nitrophenyl)methanol (2.8 g, 12.06 mmol) in a solvent mixture of dichloromethane (DCM) and acetonitrile (MeCN) (1:1, 100 mL) was added sequentially at 0 °C carbon tetrabromide (CBr4) (5.2 g, 15.68 mmol) and triphenylphosphine (PPh3) (4.1 g. 15.68 mmol). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure and the residue was purified by fast column chromatography on silica gel (petroleum ether (PE)/ethyl acetate (EA) = 50:1 to 10:1 gradient elution) to afford the target product 4-bromo-2-(bromomethyl)-1-nitrobenzene (1.1 g, 31% yield).

References

[1] Patent: WO2018/68017, 2018, A1. Location in patent: Page/Page column 154; 155; 156; 157

4-bromo-2-(bromomethyl)-1-nitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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4-bromo-2-(bromomethyl)-1-nitrobenzene Suppliers

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China
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Shanghai Haohong Pharmaceutical Co., Ltd.
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View Lastest Price from 4-bromo-2-(bromomethyl)-1-nitrobenzene manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-bromo-2-(bromomethyl)-1-nitrobenzene 35287-42-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-16

35287-42-4, 4-bromo-2-(bromomethyl)-1-nitrobenzeneRelated Search:


  • 4-bromo-2-(bromomethyl)-1-nitrobenzene
  • 5-bromo-2-nitrobenzyl bromide
  • Benzene, 4-bromo-2-(bromomethyl)-1-nitro-
  • L-Valine,5-mercapto-,methylester
  • 35287-42-4