ChemicalBook > CAS DataBase List > [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane

[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane

Product Name
[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
CAS No.
66722-57-4
Chemical Name
[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
Synonyms
Bisoprolol Impurity 8;Bisoprolol Impurity 20;Bisoprolol intermediate;Bisoprolol epoxide impurities;2-[4-(2-Isopropoxyethoxymethyl)phen;Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane;[[4-[[2-Isopropoxyethoxy]methyl]phenoxy]methyl]oxirane;[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxi;2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane;[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
CBNumber
CB01564879
Molecular Formula
C15H22O4
Formula Weight
266.33
MOL File
66722-57-4.mol
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[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane Property

Boiling point:
362.6±22.0 °C(Predicted)
Density 
1.084±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Sparingly)
form 
Oil
color 
Colourless
CAS DataBase Reference
66722-57-4
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H332Harmful if inhaled

H341Suspected of causing genetic defects

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Matrix Scientific
Product number
314180
Product name
2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane
Packaging
100.00mg
Price
$65
Updated
2026/05/19
Matrix Scientific
Product number
314180
Product name
2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane
Packaging
250.00mg
Price
$110
Updated
2026/05/19
Matrix Scientific
Product number
314180
Product name
2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane
Packaging
1.00g
Price
$359
Updated
2026/05/19
Synthonix
Product number
P66852
Product name
2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane
Purity
>98%
Packaging
100mg
Price
$70
Updated
2026/05/06
Synthonix
Product number
P66852
Product name
2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane
Purity
>98%
Packaging
250mg
Price
$120
Updated
2026/05/06
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[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Oil

Uses

An intermediate for the synthesis of Bisoprolol.

Synthesis

The synthesis of 4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane is as follows: steps. 1) Preparation of 4-hydroxybenzyl alcohol: 4-Hydroxybenzaldehyde is reduced with NaBH4. Work-up yields the product. 2) Preparation of 4-[(2-isopropoxyethoxy)methyl]phenol: 4-Hydroxybenzyl alcohol reacts with 2-isopropoxyethanol catalyzed by Amberlyst-15 resin. Work-up gives the product. 3) Preparation of the title oxirane derivative: The sodium salt of the phenol from step 2 reacts with epichlorohydrin. Toluene extraction is performed. The organic phase is treated with solid NaOH, washed, and distilled to an oil. High-vacuum distillation purifies the product.

[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane Preparation Products And Raw materials

Raw materials

Preparation Products

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[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Adamas Reagent, Ltd.
Tel
400-6009262 15618770481
Fax
021-64823266
Email
yhx@titansci.com
Country
China
ProdList
14100
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59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13770331960
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
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16100
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
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shchemsky@sina.com
Country
China
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32321
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-4000505016 13380397412
Fax
0755 28094224
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3001272453@qq.com
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China
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5157
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
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40000
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Quality Control Solutions Ltd.
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0755-66853366 13670046396
Fax
0755-28363542
Email
orders@qcsrm.com
Country
China
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Shanghai Kewel Chemical Co., Ltd.
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021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
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50
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5877
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Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
4960
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View Lastest Price from [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Bisoprolol Impurity 29 66722-57-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-28
Career Henan Chemical Co
Product
2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane 66722-57-4
Price
US $2.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2019-12-26

66722-57-4, [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxiraneRelated Search:


  • [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
  • [[4-[[2-Isopropoxyethoxy]methyl]phenoxy]methyl]oxirane
  • 2-[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
  • Oxirane, [[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]methyl]- (9CI)
  • 2-[[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]methyl]-oxira
  • Bisoprolol Impurity 20
  • 2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane
  • Bisoprolol epoxide impurities
  • Bisoprolol Impurity 8
  • 2-[4-(2-Isopropoxyethoxymethyl)phen
  • Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
  • Oxirane, 2-[[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]methyl]-
  • [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxi
  • 66722-57-4 C15H22O4 [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
  • Bisoprolol intermediate
  • 1-[4-[[2-(isopropoxy)ethoxy]methyl]phenoxy]-2,3-epoxypropane
  • 66722-57-4
  • Aromatics Compounds
  • Aromatics
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals