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Bismuth subnitrate

Product Name
Bismuth subnitrate
CAS No.
1304-85-4
Chemical Name
Bismuth subnitrate
Synonyms
BISMUTH OXYNITRATE;vicalin;vikaline;c.i.77169;novismuth;flakewhite;paintwhite;snowcal5sw;blancdefard;bismuthpaint
CBNumber
CB0163093
Molecular Formula
Bi5H9N4O22
Formula Weight
1461.99
MOL File
1304-85-4.mol
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Bismuth subnitrate Property

Melting point:
260°C
Density 
4.928
vapor pressure 
0Pa at 20℃
storage temp. 
Store at +5°C to +30°C.
solubility 
Practically insoluble in water and in ethanol (96 per cent). It dissolves in mineral acids with decomposition.
form 
Powder/Solid
color 
White
PH
3.2 (50g/l, H2O, 20℃)(slurry)
Water Solubility 
Practically insoluble in water and alcohol. Soluble in dilute HNO{3} and HCl
Sensitive 
Hygroscopic
Merck 
14,1284
Stability:
Stability Strong oxidizer - contact with combustible material may lead to fire. Incompatible with reducing agents, organic materials.
CAS DataBase Reference
1304-85-4(CAS DataBase Reference)
EPA Substance Registry System
Bismuth hydroxide nitrate oxide (Bi5(OH)9(NO3)4O) (1304-85-4)
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Safety

Hazard Codes 
O,Xi
Risk Statements 
8-36/37/38
Safety Statements 
17-26-36/37/39-36
RIDADR 
UN 1477 5.1/PG 2
WGK Germany 
3
RTECS 
EB2977000
8
TSCA 
Yes
HS Code 
2834 29 80
HazardClass 
5.1
PackingGroup 
II
Hazardous Substances Data
1304-85-4(Hazardous Substances Data)
Toxicity
infant,LDLo,oral,1gm/kg (1000mg/kg),"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 134, 1969.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H272May intensify fire; oxidizer

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P220Keep/Store away from clothing/…/combustible materials.

P221Take any precaution to avoid mixing with combustibles/…

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
310646
Product name
Bismuth(III) subnitrate
Purity
98%
Packaging
5g
Price
$71.4
Updated
2024/03/01
Sigma-Aldrich
Product number
1.01878
Product name
Bismuth(III) nitrate
Purity
alkalineforanalysisEMSURE?Reag.PhEur
Packaging
100g
Price
$212
Updated
2024/03/01
Alfa Aesar
Product number
040476
Product name
Bismuth hydroxide nitrate oxide, Bi<sub>2</sub>O<sub>3</sub> 79% min
Packaging
25g
Price
$41.5
Updated
2024/03/01
Alfa Aesar
Product number
040476
Product name
Bismuth hydroxide nitrate oxide, Bi<sub>2</sub>O<sub>3</sub> 79% min
Packaging
100g
Price
$72.7
Updated
2024/03/01
Sigma-Aldrich
Product number
B0426
Product name
Bismuth subnitrate
Purity
meets USP testing specifications
Packaging
100g
Price
$218
Updated
2024/03/01
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Bismuth subnitrate Chemical Properties,Usage,Production

Description

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent. The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.

Bismuth Subnitrate is a basic salt that contains the equivalent of not less than 79.0 percent of bismuth trioxide (Bi2O3),calculated on the dried basis.It is both odorless and tasteless, and is used in bleaching and freckle creams, and hair dyes.
Bismuth subnitrate has been used to induce metallothionein in heart tissue and kidneys and to attenuate the toxicity of Adriamycin and cisplatin compounds, respectively.

Chemical Properties

White, heavy, Slightly hygroscopic powder

Uses

manufacture of bismuth fluxes for enamels; in cosmetics.

Uses

Bismuth subnitrate (BiNO3) is used in the cosmetics industry and to make ceramic and enamel glazes.

Uses

It is used pharmaceutically in wound dressing, ointment component and as an antiacid. In cosmetics it is used as a cosmetic white pigment. Used in Ceramic glazes and enamel fluxes.

brand name

Mammol (Abbott).

Flammability and Explosibility

Non flammable

Pharmacology

Bismuth subnitrate acts as an antacid that exert protective effects on the gastric mucosa. In a double-blind endoscopically controlled study, bismuth substrate was demonstrated to be effective for symptomatic relief in duodenal ulcers. In the alcohol model of mucosal injury in the rat, bismuth substrate was shown to be cytoprotective. In a randomized clinical study consisting of patients with H. pylori-associated duodenal ulcer, adjunctive use of colloidal bismuth subnitrate in a short treatment regimen with omeprazole and clarithromycin resulted in improved eradication rate of H. pylori.

Mode of action

Based on the findings of a clinical investigation in patients with duodenal ulcer disease and healthy volunteers receiving oral bismuth subnitrate tablets, the protective effects of bismuth subnitrate may be secondary to endogenous mucosal prostaglandin (PGE2) production, which is one of the deficient factors observed in peptic ulcer disease. Antacid neutralizing activity of bismuth subnitrate was demonstrated to have a significant postprandial effect on gastric pH.

Bismuth subnitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Bismuth subnitrate Suppliers

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View Lastest Price from Bismuth subnitrate manufacturers

airuikechemical co., ltd.
Product
bismuth subnitrate 1304-85-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-09
Shaanxi Dideu Medichem Co. Ltd
Product
Bismuth subnitrate 1304-85-4
Price
US $1.00-1.00/Kg/Bag
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-30
Hebei Yanxi Chemical Co., Ltd.
Product
Bismuth subnitrate 1304-85-4
Price
US $50.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-20

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