3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE

Uses

Product Name: 3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE
CAS No.: 63857-00-1
Chemical Name: 3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE
Synonyms: N-[(3-(ANILINOMETHYLENE)-2-CHLORO-1-CYCLOHEXEN-1-YL)METHYLENE]ANILINE MONOHYDROCHLORIDE;cyclohex-2-en-1-ylidene);N-((3-[ANILINOMETHYLIDENE];N-((2-Chloro-3-((phenylimino);N-((3-(ANILINOMETHYLENE)-2-CHLORO-1-CYC&;4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE;N-((3-(anilinomethylene)-2-chloro-1-cyclo-hexen-1;3-CHLORO-2,4-TRIMETHYLENEGLUTACONDIANIL HYDROCHLORIDE;3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE;N-((3-(anilinomethylene)-2-chloro-1-cyclo-hexen-1-yl)methyle...
CBNumber: CB0169444
Molecular Formula: C20H20Cl2N2
Formula Weight: 359.29
MOL File: 63857-00-1.mol

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3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE Property

Melting point:: 224 °C (dec.)(lit.)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMF: 0.25 mg/ml; DMSO: 3 mg/ml; Ethanol: 1 mg/ml
form: A solid
InChI: InChI=1S/C20H19ClN2.ClH/c21-20-16(14-22-18-10-3-1-4-11-18)8-7-9-17(20)15-23-19-12-5-2-6-13-19;/h1-6,10-15,22H,7-9H2;1H/b16-14?,23-15+;
InChIKey: VFKQWKQWRNVXTA-LPYKZFQHSA-N
SMILES: C(=C1CCCC(/C=N/C2C=CC=CC=2)=C1Cl)NC1C=CC=CC=1.Cl

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 407232
Product name: N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline monohydrochloride
Purity: 94%
Packaging: 5g
Price: $389
Updated: 2025/07/31

Cayman Chemical

Product number: 30560
Product name: N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline (hydrochloride)
Packaging: 500mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 30560
Product name: N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline (hydrochloride)
Packaging: 5g
Price: $335
Updated: 2024/03/01

Cayman Chemical

Product number: 30560
Product name: N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline (hydrochloride)
Packaging: 1g
Price: $130
Updated: 2024/03/01

TRC

Product number: C609773
Product name: N-((2-Chloro-3-((phenylimino)methyl)cyclohex-2-en-1-ylidene)methyl)anilineHydrochloride
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

N-((2-Chloro-3-((phenylimino)methyl)cyclohex-2-en-1-ylidene)methyl)aniline hydrochloride is a useful research chemical.

Description

3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE is a building block, it has been used in the synthesis of cyanine-containing dyes.

Uses

diagnostic assay manufacturing
hematology
histology

Synthesis

108-94-1

68-12-2

62-53-3

63857-00-1

Phosphoryl chloride (11.0 mL, 120 mmol) was slowly added dropwise to anhydrous N,N-dimethylformamide (13.0 mL, 170 mmol) via a pressure-balanced addition funnel at 0 °C under stirring. After the dropwise addition, stirring was continued for 30 min. Subsequently, cyclohexanone (5.50 mL, 53.0 mmol) was added to the reaction system and the mixture was heated to reflux and maintained for 1 hour. After completion of the reaction, the system was cooled to 20 °C. At this temperature, a pre-formulated aniline/ethanol [1:1 (v/v), 180 mL] mixture was slowly added dropwise to the reaction mixture. After the dropwise addition was completed, the reaction was vigorously stirred at 20 °C for 30 min. The resulting dark purple reaction mixture was poured into a pre-cooled mixed solution of H2O/HCl [10:1 (v/v), 110 mL] and subsequently placed in an ice bath for 2 hours to crystallize. The crystals formed were collected by filtration, washed sequentially with cold water and ether, and finally dried under vacuum to afford the target product N-[(3-(anilinoiminomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline hydrochloride (14.8 g, 97% yield) as a dark purple solid. The product was characterized by 1H NMR (d6-DMSO, 250 MHz): δ 11.2 (s, 2H, NH), 8.55 (d, J = 14.0 Hz, 2H, CH olefin), 7.68 (d, J = 5.0 Hz, 4H, Ar-H), 7.44 (t, J = 7.0 Hz, 4H, Ar-H), 3.03 (t, J = 6.0 Hz. 4H, CH2-CH2), 2.05-1.98 (m, 2H, CH2-CH2).IR (ATR) spectrum showed characteristic absorption peaks located at 1609 (C=N), 1562, 1457, 1267, 1179, 752, 683, 565 cm-1.Mass spectrometry (ESI) analysis showed m/z: 323.22 [M+]. The melting point was determined to be 226-231 °C.

References

[1] Journal of Sulfur Chemistry, 2014, vol. 35, # 1, p. 42 - 56
[2] Journal of Fluorescence, 2012, vol. 22, # 2, p. 719 - 727
[3] Patent: US2013/149252, 2013, A1. Location in patent: Paragraph 0135
[4] Patent: US9370589, 2016, B2. Location in patent: Page/Page column 23; 24
[5] Patent: EP1223197, 2002, A2. Location in patent: Example 18

3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE Suppliers

China 77 China Hong Kong 1 Germany 4 India 1 Switzerland 1 Ukraine 4 United Kingdom 1 United States 12 Global 101

INTATRADE GmbH

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View Lastest Price from 3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: 3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE 63857-00-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

63857-00-1, 3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDERelated Search:

N-METHYL-O-TOLUIDINE 3-Chloro-2-methylpropene Glutacondianil hydrochloride 1-CHLORO-2-METHYL-1-PROPENE 3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE

N-[(2-CHLORO-1-PHENYLIMINOMETHYL-1-CYCLOHEXENE-3-YLIDENE)METHYL]ANILINE HYDROCHLORIDE

N-[(3-(ANILINOMETHYLENE)-2-CHLORO-1-CYCLOHEXEN-1-YL)METHYLENE]ANILINE MONOHYDROCHLORIDE

N-((3-[ANILINOMETHYLIDENE]-2-CHLORO-1-CYCLOHEXEN-1-YL)METHYLIDENE)ANILINE HYDROCHLORIDE

3-CHLORO-2,4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE

BENZENAMINE, N-[[2-CHLORO-3-[(PHENYLAMINO)METHYLENE]-1-CYCLOHEXEN-1-YL]METHYLENE]-, MONOHYDROCHLORIDE

N-((2-Chloro-3-((phenylimino)methyl)cyclohex-2-en-1-ylidene)methyl)aniline hydrochloride

N-((e)-(2-chloro-3-((e)-(phenylimino)methyl)cyclohex-2-enylidene)methyl)aniline hydrochloride

cyclohex-2-en-1-ylidene)

N-((2-Chloro-3-((phenylimino)

N-((2-CHLORO-3-((PHENYLIMINO)METHYL)CYCLOHEX-2-EN-1-YLIDENE)METHYL)ANILINE HCL

N-((3-[ANILINOMETHYLIDENE]

N-((3-(anilinomethylene)-2-chloro-1-cyclo-hexen-1

N-2-chloro-3-(phenylamino)methylene-1-cyclohexen-1-ylmethylene-Benzenaminemonohydrochloride

N-((3-(ANILINOMETHYLENE)-2-CHLORO-1-CYC&

N-((3-(ANILINOMETHYLENE)-2-CHLORO-1-CYCL O-HEXEN-1-YL)METHYLENE)ANILINE HCL, 97%

N-[(2-Chloro-1-phenyliminomethyl-1-cyclohexene-3-ylidene)methyl]anilineHCl

3-CHLORO-2,4-TRIMETHYLENEGLUTACONDIANIL HYDROCHLORIDE

N-[[2-chloro-3-(phenyliminomethyl)-1-cyclohex-2-enylidene]methyl]aniline hydrochloride

N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline monohydrochloride 94%

N-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline (hydrochloride)

4-TRIMETHYLENENGLUTACONDIANIL HYDROCHLORIDE

N-((3-(anilinomethylene)-2-chloro-1-cyclo-hexen-1-yl)methyle...

N-[(E)-[2-chloro-3-(phenyliminomethyl)cyclohex-2-en-1-ylidene]methyl]aniline

Benzenamine, N-[[2-chloro-3-[(phenylamino)methylene]-1-cyclohexen-1-yl]methylene]-, hydrochloride (1:1)

N-[[2-Chloro-3-[(phenylamino)methylene]-1-cyclohexenyl]methylene]aniline Hydrochloride

N-[{2-Chloro-3-[(phenylimino)methyl]-2-cyclohexen-1-ylidene}methyl]aniline hydrochloride

<i>N</i>-[(3-(Anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline monohydrochloride

63857-00-1

C20H20Cl2N2

C20H19ClN2HCl

C20H20N2Cl2

A

Stains and Dyes

Stains&Dyes, A to