CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
- Product Name
- CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
- CAS No.
- 130465-39-3
- Chemical Name
- CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
- Synonyms
- A 68930;A68930HCl;A 68930 hydrochlorid;A 68930 HYDROCHLORIDE;A-68930 hydrochloride (A68930);cis-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride;(1R,3S)-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride;(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran;1-(aminomethyl)-3,4-dihydro-3-phenyl-1H-2-Benzopyran-5,6-diol hydrochloride;cis-(±)-1-Aminoethyl-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
- CBNumber
- CB0174886
- Molecular Formula
- C16H18ClNO3
- Formula Weight
- 307.77
- MOL File
- 130465-39-3.mol
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Property
- storage temp.
- −20°C
- solubility
- H2O: ~9 mg/mL, soluble
- form
- solid
- color
- off-white
- Water Solubility
- Soluble to 50 mM in water
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1534
- Product name
- A-68930 hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $162
- Updated
- 2021/12/16
- Product number
- 1534
- Product name
- A-68930 hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $682
- Updated
- 2021/12/16
- Product number
- A965318
- Product name
- A-68930 hydrochloride
- Packaging
- 1mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 254474
- Product name
- A 68930 hydrochloride
- Packaging
- 10mg
- Price
- $446
- Updated
- 2021/12/16
- Product number
- B6779
- Product name
- A-68930 hydrochloride
- Packaging
- 10mg
- Price
- $234
- Updated
- 2021/12/16
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
A 68930 Hydrochloride is a potent and selective agonist at the D1-like dopamine receptor. It demontrated neuroprotective and anti-stress effects in rat model (1,2).
Biological Activity
Potent and selective D 1 -like dopamine receptor agonist (EC 50 values are 2.1 and 3910 nM for D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo .
storage
Desiccate at +4°C
References
[1]. kebabian jw, briggs c, britton dr, et al. a68930: a potent and specific agonist for the d-1 dopamine receptor. am j hypertens, 1990, 3(6 pt 2): 40s-42s.
[2]. salmi p. independent roles of dopamine d1 and d2/3 receptors in rat thermoregulation. brain res, 1998, 781(1-2): 188-193.
[3]. deveney am, waddington jl. psychopharmacological distinction between novel full-efficacy "d1-like" dopamine receptor agonists. pharmacol biochem behav, 1997, 58(2): 551-558.
[4]. rasheed n, ahmad a, al-sheeha m, et al. neuroprotective and anti-stress effect of a68930 in acute and chronic unpredictable stress model in rats. neurosci lett, 2011, 504(2): 151-155.
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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