4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE

Product Name: 4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE
CAS No.: 178803-51-5
Chemical Name: 4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE
Synonyms: SNC 162;4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE;4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide;Benzamide, 4-[(S)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl]phenylmethyl]-N,N-diethyl-
CBNumber: CB0189541
Molecular Formula: C27H37N3O
Formula Weight: 419.6
MOL File: 178803-51-5.mol

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4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE Property

Boiling point:: 536.4±50.0 °C(Predicted)
Density: 1.027
storage temp.: Store at RT
solubility: Soluble to 100 mM in 1eq. HCl
form: Powder
pka: 7.28±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1529
Product name: SNC162
Purity: ≥99%(HPLC)
Packaging: 10
Price: $255
Updated: 2021/12/16

Tocris

Product number: 1529
Product name: SNC162
Purity: ≥99%(HPLC)
Packaging: 50
Price: $1050
Updated: 2021/12/16

TRC

Product number: S590050
Product name: SNC162
Packaging: 10mg
Price: $775
Updated: 2021/12/16

Usbiological

Product number: 256709
Product name: SNC 162
Packaging: 10mg
Price: $516
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019233
Product name: 4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE
Purity: 95.00%
Packaging: 10MG
Price: $532.35
Updated: 2021/12/16

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4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE Chemical Properties,Usage,Production

Uses

Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. SNC 162 is a selective δ-opioid receptor agonist.

Definition

ChEBI: 4-[(S)-[(2S,5R)-2,5-dimethyl-4-prop-2-enyl-1-piperazinyl]-phenylmethyl]-N,N-diethylbenzamide is a diarylmethane.

Biological Activity

Potent and selective non-peptide δ -opioid receptor agonist (K i = 0.63 nM). Displays > 8000-fold selectivity over μ -opioid receptors and is centrally active following systemic administration in vivo .

IC 50

δ Opioid Receptor/DOR

storage

Store at RT

4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE Suppliers

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178803-51-5, 4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDERelated Search:

[(4-METHYLPHENYL)PHENYLMETHYL]PIPERAZINE 4-[(AR*)-ALPHA-((2S*,5R*)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-HYDROXYBENZYL]-N,N-DIETHYLBENZAMIDE N-METHYL-N-[4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZYL]AMINE (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE 4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE SNC 80

4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide

SNC 162

4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE

Benzamide, 4-[(S)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl]phenylmethyl]-N,N-diethyl-

178803-51-5

Opioid receptor and opioid-like receptor