ChemicalBook > CAS DataBase List > 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE

3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE

Product Name
3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE
CAS No.
61160-18-7
Chemical Name
3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE
Synonyms
3-(Benzyloxy)-2-Methylpyridin-4(1H)-one;Kojic Impurity 11;Avobenzone Impurity 4;3-BENZYLOXY-2-METHYL-4(1H)PYRIDONE;3-BENZYLOXY-2-METHYL-1H-PYRIDIN-4-ONE;3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE;2-Methyl-3-phenylmethoxy-1H-pyridin-4-one;4(1H)-Pyridinone, 2-methyl-3-(phenylmethoxy)-
CBNumber
CB0199337
Molecular Formula
C13H13NO2
Formula Weight
215.25
MOL File
61160-18-7.mol
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3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE Property

Melting point:
171-173°C
storage temp. 
Sealed in dry,Room Temperature
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Safety

HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
045049
Product name
3-(Benzyloxy)-2-methyl-4(1H)-pyridinone
Packaging
500.00mg
Price
$41
Updated
2026/05/18
Matrix Scientific
Product number
045049
Product name
3-(Benzyloxy)-2-methyl-4(1H)-pyridinone
Packaging
1.00g
Price
$63
Updated
2026/05/18
Matrix Scientific
Product number
045049
Product name
3-(Benzyloxy)-2-methyl-4(1H)-pyridinone
Packaging
5.00g
Price
$219
Updated
2026/05/18
Crysdot
Product number
CD11093991
Product name
3-(Benzyloxy)-2-methylpyridin-4(1H)-one
Purity
95+%
Packaging
10g
Price
$325
Updated
2026/05/26
Crysdot
Product number
CD11093991
Product name
3-(Benzyloxy)-2-methylpyridin-4(1H)-one
Purity
95+%
Packaging
25g
Price
$699
Updated
2026/05/26
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3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE Chemical Properties,Usage,Production

Synthesis

61049-69-2

61160-18-7

General procedure for the synthesis of 3-(benzyloxy)-2-methyl-4H-pyran-4-one from 3-(benzyloxy)-2-methyl-4H-pyran-4-one: To a solution of 3-(benzyloxy)-2-methyl-4H-pyran-4-one (13.8 g, 0.064 mol) in ethanol (25 mL) was added aqueous ammonia solution (50 mL), and the reaction was carried out at reflux overnight. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in water and the pH was adjusted with concentrated hydrochloric acid to 1. The resulting aqueous phase was washed with ethyl acetate (3 x 25 mL), followed by adjusting the pH with 2 M sodium hydroxide solution to 10. The aqueous phase was then extracted with chloroform (3 x 1 L), and the organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was recrystallized with a solvent mixture of methanol/ether to give brown cubic crystals with a melting point of 162-164 °C. The product was extracted with chloroform (3×L) and dried with anhydrous sodium sulfate. The yield was 75%. The product was characterized by 1H NMR (CDCl3): δ 2.15 (3H, s, CH3), 5.03 (2H, s, CH2Ph), 6.35 (1H, d, J = 6.9Hz, 5-H), 7.25-7.31 (5H, m, Ph-H), 7.39 (1H, d, J = 6.9Hz, 6-H). The molecular formula is C13H13NO2.

References

[1] Journal of Medicinal Chemistry, 1993, vol. 36, # 17, p. 2448 - 2458
[2] Journal of Heterocyclic Chemistry, 1992, vol. 29, # 4, p. 1017 - 1019
[3] Tetrahedron, 2001, vol. 57, # 16, p. 3479 - 3486
[4] Patent: WO2006/103463, 2006, A1. Location in patent: Page/Page column 9; Figure 2
[5] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 3, p. 1285 - 1297

3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE Suppliers

China 55 Germany 1 India 1 United Kingdom 4 United States 9 Global 70
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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market03@meryer.com
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China
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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86-027-87531808
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sales@chemwish.com
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China
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SuZhou ShiYa Biopharmaceuticals, Inc.
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86(512)5235 6881
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400-6206333 13167063860
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021-50323701
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China
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Shanghai Macklin Biochemical Co.,Ltd.
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15221275939; 15221275939
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shenlinxing@macklin.cn
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China
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ShangHai Yuchuan Pharmaceutical Technology Co., Ltd.
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02161555100
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China
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Cool Pharm, Ltd
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021-60455363 18019463053
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sales@coolpharm.com
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China
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Shanghai Chenzhu Pharmaceutical Co., Ltd.
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13162380607
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QQ:1696175688
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1696175688@qq.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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View Lastest Price from 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE manufacturers

Career Henan Chemical Co
Product
3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE 61160-18-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-31

61160-18-7, 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONERelated Search:

3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE 1-BENZYL-3-[(2,6-DICHLOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 1-(2-CHLORO-6-FLUOROBENZYL)-3-[(2,6-DICHLOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-[(2,6-DICHLOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-METHYL-4(1H)-PYRIDINONE 3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-1-(3-NITRO-2-PYRIDINYL)-4(1H)-PYRIDINONE 3-[(2,6-DICHLOROBENZYL)OXY]-1-(4-FLUOROBENZYL)-2-METHYL-4(1H)-PYRIDINONE 1-(4-CHLOROBENZYL)-3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 3-[(4-CHLOROBENZYL)OXY]-1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-METHYL-4(1H)-PYRIDINONE 1-BENZYL-3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-1-(4-METHYLBENZYL)-4(1H)-PYRIDINONE 3-[(2,6-DICHLOROBENZYL)OXY]-2-METHYL-1-(4-METHYLBENZYL)-4(1H)-PYRIDINONE 1-(2-CHLORO-6-FLUOROBENZYL)-3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-1-(4-FLUOROBENZYL)-2-METHYL-4(1H)-PYRIDINONE 3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 3-[(2-CHLORO-6-FLUOROBENZYL)OXY]-2-METHYL-1-(4-NITROBENZYL)-4(1H)-PYRIDINONE 1-(4-CHLOROBENZYL)-3-[(2,6-DICHLOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE 3-[(2,6-DICHLOROBENZYL)OXY]-2-METHYL-4(1H)-PYRIDINONE

  • 3-BENZYLOXY-2-METHYL-1H-PYRIDIN-4-ONE
  • 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE
  • 4(1H)-Pyridinone, 2-methyl-3-(phenylmethoxy)-
  • 3-(Benzyloxy)-2-Methylpyridin-4(1H)-one
  • 3-BENZYLOXY-2-METHYL-4(1H)PYRIDONE
  • 2-Methyl-3-phenylmethoxy-1H-pyridin-4-one
  • Kojic Impurity 11
  • Avobenzone Impurity 4
  • 61160-18-7