4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- Product Name
- 4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- CAS No.
- 710972-40-0
- Chemical Name
- 4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- Synonyms
- 1-Boc-4-(2-methoxyethylamino)piperidine;N-Boc-4-(2-methoxyethylamino)-piperidine;1-Boc-N-(2-methoxyethyl)piperidin-4-amine;TERT-BUTYL 4-[(2-METHOXYETHYL)AMINO]PIPERIDINE-1-CARBOXYLATE;4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;4-(2-methoxyethylamino)piperidine-1-carbpxylic acid tert-butyl ester;4-(2-methoxyethylamino)-1-piperidinecarboxylic acid tert-butyl ester;1,1-diMethylethyl 4-([2-(Methyloxy)ethyl]aMino)-1-piperidinecarboxylate;4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, 95+%;1-Piperidinecarboxylicacid, 4-[(2-methoxyethyl)amino]-, 1,1-dimethylethyl ester
- CBNumber
- CB0203665
- Molecular Formula
- C13H26N2O3
- Formula Weight
- 258.36
- MOL File
- 710972-40-0.mol
4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Property
- Boiling point:
- 337.6±32.0 °C(Predicted)
- Density
- 1.03±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 9.01±0.20(Predicted)
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 212245
- Product name
- 1-Boc-4-(2-Methoxyethylamino)piperidine
- Purity
- 90%
- Packaging
- 250mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FB154169
- Product name
- 1-Boc-4-(2-Methoxyethylamino)piperidine
- Packaging
- 250mg
- Price
- $97.5
- Updated
- 2021/12/16
- Product number
- FB154169
- Product name
- 1-Boc-4-(2-Methoxyethylamino)piperidine
- Packaging
- 500mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- 118855
- Product name
- 1-Boc-4-(2-Methoxyethylamino)piperidine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- FB154169
- Product name
- 1-Boc-4-(2-Methoxyethylamino)piperidine
- Packaging
- 1g
- Price
- $295
- Updated
- 2021/12/16
4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Chemical Properties,Usage,Production
Synthesis
79099-07-3
109-85-3
710972-40-0
To a solution of N-tert-butoxycarbonyl-4-piperidone (1 g, 5.0 mmol) in methanol (20 mL) was sequentially added acetic acid (0.3 mL, 5.0 mmol), 2-methoxyethylamine (0.44 mL, 5.0 mmol), and sodium cyanoborohydride (346 mg, 5.5 mmol). The reaction mixture was stirred at 25°C for 12 hours. After completion of the reaction, the reaction solution was diluted with aqueous sodium carbonate and extracted with ethyl acetate several times. The organic phases were combined, concentrated and purified by silica gel column chromatography (eluent: dichloromethane/methanol, 0-10% gradient) to afford tert-butyl 4-(2-methoxyethylamino)piperidine-1-carboxylate (1.2 g, 93%) as a yellow oil.LC/MS (ES) m/e 259 (M+H)+.
References
[1] Patent: WO2007/16610, 2007, A2. Location in patent: Page/Page column 49; 50
[2] Patent: WO2017/21730, 2017, A1. Location in patent: Page/Page column 59
[3] Patent: WO2006/46031, 2006, A1. Location in patent: Page/Page column 56; 58
[4] Patent: CN107814792, 2018, A. Location in patent: Paragraph 0223; 0224
[5] Patent: WO2007/122410, 2007, A1. Location in patent: Page/Page column 94-95; 101-102
4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER manufacturers
- Product
- 4-(2-METHOXYETHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 710972-40-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500KG
- Release date
- 2018-08-19