ChemicalBook > CAS DataBase List > 1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester

1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester

Product Name
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
CAS No.
54280-71-6
Chemical Name
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
Synonyms
Nemadipine-A;NemadipineA,Nemadipine A;Nemadipine-A - CAS 54280-71-6 - Calbiochem;Nemadipine A, L-type calcium channel protein inhibitor;1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-, 3,5-diethyl ester
CBNumber
CB02097051
Molecular Formula
C19H18F5NO4
Formula Weight
419.34
MOL File
54280-71-6.mol
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1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Property

storage temp. 
−20°C
solubility 
DMSO:20.0(Max Conc. mg/mL);47.69(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);35.77(Max Conc. mM)
Methanol:100.0(Max Conc. mg/mL);238.46(Max Conc. mM)
form 
Pale-yellow solid
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21689
Product name
Nemadipine A
Purity
≥98%
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
21689
Product name
Nemadipine A
Purity
≥98%
Packaging
10mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
21689
Product name
Nemadipine A
Purity
≥98%
Packaging
25mg
Price
$302
Updated
2024/03/01
Cayman Chemical
Product number
21689
Product name
Nemadipine A
Purity
≥98%
Packaging
50mg
Price
$570
Updated
2024/03/01
TRC
Product number
N389803
Product name
Nemadipine-A
Packaging
5mg
Price
$165
Updated
2021/12/16
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1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Chemical Properties,Usage,Production

Uses

Nemadipine-A is a cell permeable L-type calcium channel protein inhibitor.

Definition

ChEBI: Nemadipine-A is a dihydropyridine that is that is 1,4-dihydropyridine which is substituted at positions 2 and 6 by methyl groups, at positions 3 and 5 by ethoxycarbonyl groups, and at position 4 by a pentafluorophenyl group. An L-type calcium channel alpha1-subunit antagonist. When exposed to the microscopic soil nematode Caenorhabditis elegans, nemadipine-A induces a variety of defects including those affecting morphology and egg laying. It has a role as a calcium channel blocker. It is a dihydropyridine, a diester, a member of pentafluorobenzenes, an ethyl ester and a member of dicarboxylic acids and O-substituted derivatives.

1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Suppliers

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54280-71-6, 1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl esterRelated Search:


  • 1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
  • Nemadipine-A
  • Nemadipine-A - CAS 54280-71-6 - Calbiochem
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-, 3,5-diethyl ester
  • NemadipineA,Nemadipine A
  • Nemadipine A, L-type calcium channel protein inhibitor
  • 54280-71-6
  • C19H18F5NO4