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Aprepitant-d4

Product Name
Aprepitant-d4
CAS No.
1133387-60-6
Chemical Name
Aprepitant-d4
Synonyms
Aprepitant-d4;[2H4]-Aprepitant;5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one;Aprepitant D4Q: What is Aprepitant D4 Q: What is the CAS Number of Aprepitant D4 Q: What is the storage condition of Aprepitant D4 Q: What are the applications of Aprepitant D4
CBNumber
CB02104032
Molecular Formula
C23H17D4F7N4O3
Formula Weight
538.451309512
MOL File
1133387-60-6.mol
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Aprepitant-d4 Property

Melting point:
242-244°C
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25232
Product name
Aprepitant-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
500μg
Price
$194
Updated
2021/12/16
Cayman Chemical
Product number
25232
Product name
Aprepitant-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
1mg
Price
$349
Updated
2021/12/16
TRC
Product number
A729803
Product name
Aprepitant-d4
Packaging
1mg
Price
$215
Updated
2021/12/16
TRC
Product number
A729803
Product name
Aprepitant-d4
Packaging
10mg
Price
$1695
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RDL0006664
Product name
APREPITANT-D4
Purity
95.00%
Packaging
5MG
Price
$502.01
Updated
2021/12/16
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Aprepitant-d4 Chemical Properties,Usage,Production

Uses

Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting.

Aprepitant-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

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Aprepitant-d4 Suppliers

United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1133387-60-6, Aprepitant-d4Related Search:


  • Aprepitant-d4
  • 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
  • 5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
  • [2H4]-Aprepitant
  • Aprepitant D4Q: What is Aprepitant D4 Q: What is the CAS Number of Aprepitant D4 Q: What is the storage condition of Aprepitant D4 Q: What are the applications of Aprepitant D4
  • 1133387-60-6
  • C23H17F7N4O3D4
  • Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals