ChemicalBook > CAS DataBase List > 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE

8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE

Product Name
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
CAS No.
23583-48-4
Chemical Name
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
Synonyms
B-cAMP;8-BR-CAMP;8-BROMO-CAMP;8-Br-A-3:5-MP;8-BR-CAMP,98+%;8-Bromocyclic AMP;Cyclic amp, 8-bromo;-CyclicMonophosphate;8-Bromo-cyclic 3',5'-amp;8-bromo-3',5'-cyclic AMP
CBNumber
CB0218315
Molecular Formula
C10H11BrN5O6P
Formula Weight
408.1
MOL File
23583-48-4.mol
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8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Property

Melting point:
254 °C (dec.) (lit.)
Boiling point:
741.9±70.0 °C(Predicted)
Density 
2.80±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
aqueous base: soluble
pka
0.95±0.60(Predicted)
form 
Powder
color 
Pale Brown
Sensitive 
Hygroscopic
BRN 
591930
InChI
1S/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
InChIKey
DVKQVRZMKBDMDH-UUOKFMHZSA-N
SMILES
Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Br)nc12
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
3-10
HS Code 
29349990
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B5386
Product name
8-Bromoadenosine 3′,5′-cyclic monophosphate
Purity
≥97% (HPLC)
Packaging
5mg
Price
$41.13
Updated
2025/07/31
Sigma-Aldrich
Product number
B5386
Product name
8-Bromoadenosine 3′,5′-cyclic monophosphate
Purity
≥97% (HPLC)
Packaging
25mg
Price
$146
Updated
2025/07/31
Cayman Chemical
Product number
18141
Product name
8-bromo-Cyclic AMP
Purity
≥95%
Packaging
10mg
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
18141
Product name
8-bromo-Cyclic AMP
Purity
≥95%
Packaging
25mg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
B5386
Product name
8-Bromoadenosine 3′,5′-cyclic monophosphate
Purity
≥97% (HPLC)
Packaging
100mg
Price
$437
Updated
2025/07/31
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8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

8-Bromoadenosine 3′,5′-cyclic monophosphate has been used:

  • to treat H295R cells as positive controls for CYP19 induction
  • as a membrane permeable cAMP analog to study its effect on short-circuit current (Isc)
  • to investigate its potential as an inducer of differentiation in Wharton′s jelly-derived mesenchymal stem cells (WJ-MSCs)

Definition

ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase.

Biochem/physiol Actions

8-bromo-adenosine?3′,5′-cyclic?monophosphate?(8-bromo-cAMP), added to hepatocytes during plating helps to increase the acquisition of beta-adrenoceptors.

in vivo

8-Bromo-cAMP (60 mg/kg/day, i.p., 7 days) reduces tumor in CT26 tumor mice[4].

Animal Model:CT26 tumor mice[4]
Dosage:60 mg/kg/day
Administration:i.p., 7 days
Result:Decreases amounts of primary CRC tumor nodules and liver metastases.
Reduces vasculogenic mimicry (PAS–CD31 staining of colorectal and intestinal tumors).
Inhibits cAMP and VEGF expression, increases expression of PKA in tumor tissues.

8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Suppliers

China 88 Germany 2 India 3 Switzerland 1 United Kingdom 2 United States 7 Global 103
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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400-9205774
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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View Lastest Price from 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE manufacturers

Career Henan Chemical Co
Product
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE 23583-48-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons
Release date
2020-03-04

23583-48-4, 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATERelated Search:

8-BROMOADENOSINE 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT HYDRATE (7-DIMETHYLAMINOCOUMARIN-4-YL)METHYL-8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE, HYDRATE 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT,8-bromoadenosine 3:5-cyclic*monophosphate sodiu BCMCM-CAGED 8-BR-CAMP, 2,5-HYDRATE

  • 8-BR-CAMP
  • 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
  • 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE
  • 8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE
  • 8-BROMOADENOSINE-3',5'-CYCLOPHOSPHORIC ACID
  • 8-BROMO-ADENOSINE CYCLIC 3',5'-HYDROGEN PHOSPHATE
  • 8-BROMO-CAMP
  • 8-BROMOADENOSINE 3' 5'-CYCLIC
  • 8-BROMOADENOSINE-3-5-CYCLICMONOPHOSPHATE FREE ACID
  • 8-Bromo Cyclic Adenosine Monophosphate
  • 8-Bromoadenosine-3'',-5''-cyclic monophosphoric acid
  • 8-BR-CAMP,98+%
  • 8-Bromoadenosine 3',5'-phosphoric acid
  • 8-Bromocyclic AMP
  • B-cAMP
  • 8-Bromoadenosine 3',5'-monophosphate
  • 8-Bromoadenosine cyclic 3',5'-phosphate
  • 8-Bromo-cyclic 3',5'-amp
  • Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate)
  • Cyclic 8-bromoadenosine 3',5'-monophosphate
  • Cyclic amp, 8-bromo
  • 8-Br-A-3:5-MP
  • 8-bromo-3',5'-cyclic AMP
  • -CyclicMonophosphate
  • 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE USP/EP/BP
  • 8-?bromo-?,cyclic3',?5'-?(hydrogenphosphate)Adenosine
  • (4aR,6R,7R,7aS)-6-(6-Amino-8-bromo-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide
  • 8-Bromoadenosine3',5'-cyclicmonophosphate
  • 23583-48-4
  • C10H11BrN5O6PNa
  • C10H11BrN5O6P
  • G Proteins and Cyclic Nucleotides
  • Cyclic Nucleotide Metabolism
  • Cyclic Nucleotides and Analogs
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology