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NERIIFOLIN

Product Name
NERIIFOLIN
CAS No.
466-07-9
Chemical Name
NERIIFOLIN
Synonyms
NERIIFOLIN;17α-Neriifolin;17β-Neriifolin;xy)-14-hydroxy-;17beta-Neriifolin;NERIIFOLIN USP/EP/BP;digitoxigenin+thevetose;14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside);3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide;3β-[(3-O-Methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
CBNumber
CB0229805
Molecular Formula
C30H46O8
Formula Weight
534.68
MOL File
466-07-9.mol
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NERIIFOLIN Property

Melting point:
218-225°C
alpha 
D23 -50.2° (CH3OH)
storage temp. 
2-8°C
solubility 
Chloroform(Slightly), DMSO(Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
Pale Yellow
biological source
plant
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
FH4906100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
N390105
Product name
17β-Neriifolin
Packaging
5mg
Price
$185
Updated
2021/12/16
ChemScene
Product number
CS-0144224
Product name
Neriifolin
Purity
≥96.0%
Packaging
5mg
Price
$450
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CRB0003776
Product name
14-HYDROXY-5BETA-CARD-20(22)-ENOLIDE 3-(6-DEOXY-3-O-METHYL-ALPHA-L-GLUCOPYRANOSIDE)
Purity
95.00%
Packaging
5MG
Price
$501.88
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
66373
Product name
17β-Neriifolin
Packaging
5mg
Price
$650
Updated
2021/12/16
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NERIIFOLIN Chemical Properties,Usage,Production

Uses

17β-neriifolin could be considered a candidate for the treatment of hepatocellular carcinoma. It can also work as an inhibitor of hERG channel trafficking.

Definition

ChEBI: A cardenolide glycoside that is digitoxigenin in which the hydroxy goup at position 3 has been converted to its (6-deoxy-3-O-methyl-alpha-L-glucopyranoside derivative. Found in the seeds of Cerbera odollamand in Thevetia ahouia and Thevitia neriifolia.

Biological Activity

Neriifolin has a role as a cardiotonic drug, a toxin and a neuroprotective agent.

NERIIFOLIN Preparation Products And Raw materials

Raw materials

Preparation Products

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466-07-9, NERIIFOLINRelated Search:


  • 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside), 3-([6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxy)-14-hydroxy-5β-card-20(22)-enolide]
  • NERIIFOLIN
  • digitoxigenin+thevetose
  • xy)-14-hydroxy-
  • (3-beta,5-beta)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
  • (5beta)-3beta-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
  • (17R)-3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14-hydroxy-5β,14β-carda-20(22)-enolide
  • 17α-Neriifolin
  • 3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14β-hydroxy-5β-carda-20(22)-enolide
  • 3β-[(3-O-Methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
  • 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
  • 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside)
  • Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
  • 17β-Neriifolin
  • NERIIFOLIN USP/EP/BP
  • 17beta-Neriifolin
  • 466-07-9