ChemicalBook > CAS DataBase List > AFLATOXIN B2

AFLATOXIN B2

Product Name
AFLATOXIN B2
CAS No.
7220-81-7
Chemical Name
AFLATOXIN B2
Synonyms
AF B2;2,3,6aB1;8,9,9aB1;AFLATOXIN B2;Aflatoxine B2;AFLATOXIN B2(RG);Aflatoxin B2;AF B2;dihydroaflatoxinb1;Dihydroaflatoxin B1;Dihydroafflatoxin B1
CBNumber
CB0236746
Molecular Formula
C17H14O6
Formula Weight
314.29
MOL File
7220-81-7.mol
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AFLATOXIN B2 Property

Melting point:
286-289 °C
alpha 
D -492° (c = 0.1 in CHCl3)
Boiling point:
373.98°C (rough estimate)
Density 
1.2564 (rough estimate)
refractive index 
1.4800 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
solubility 
DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12 mg/ml
form 
Solid
color 
White to off-white
Water Solubility 
15mg/L(temperature not stated)
Merck 
13,180
BRN 
1355115
LogP
1.802 (est)
CAS DataBase Reference
7220-81-7
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Safety

Hazard Codes 
T+,T,F,Xn
Risk Statements 
45-26/27/28-39/23/24/25-23/24/25-11-65-48/23/24/25-36/38-46-36-20/21/22
Safety Statements 
53-36-45-36/37-26-62-28-16
RIDADR 
UN 3462 6.1/PG 1
WGK Germany 
3
RTECS 
GY1722000
10
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
29322090
Hazardous Substances Data
7220-81-7(Hazardous Substances Data)
Toxicity
LD50 orally in day old duckling: 84.8 mg/50 gm body wt (Carnaghan)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H340May cause genetic defects

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CRM46324
Product name
Aflatoxin B2 solution
Purity
certified reference material, 3?μg/mL in benzene:acetonitrile (98:2), ampule of 1?mL
Packaging
1mL
Price
$51.78
Updated
2024/03/01
Sigma-Aldrich
Product number
34034
Product name
Aflatoxin B2 solution
Purity
0.5?μg/mL in acetonitrile, analytical standard
Packaging
2ml
Price
$339
Updated
2024/03/01
Sigma-Aldrich
Product number
32755
Product name
Aflatoxin B2
Purity
reference material
Packaging
5mg
Price
$2070
Updated
2024/03/01
Cayman Chemical
Product number
11294
Product name
Aflatoxin B2
Purity
≥98%
Packaging
1mg
Price
$72
Updated
2024/03/01
Cayman Chemical
Product number
11294
Product name
Aflatoxin B2
Purity
≥98%
Packaging
5mg
Price
$283
Updated
2024/03/01
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AFLATOXIN B2 Chemical Properties,Usage,Production

Chemical Properties

The aflatoxins are a group of molds produced by the fungus Aspergillus flavus. They are natural contaminants of fruits, vegetables, and grains. They are also described as a series of condensed ring heterocyclic compounds. They form colorless to pale yellow crystals. Practically insoluble in water.

Chemical Properties

off-white powder

Uses

Aflatoxin B2 is the minor analogue of the blue fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.

Uses

Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects.

Uses

Aflatoxins are naturally occuring mycotoxins produced by various species of the mold Aspergillus, which can be found in legumes, corn, soybeans, rice, milk, and cheese. They are highly carcinogenic substances that are metabolized by the liver to a reactive epoxide intermediate, which produces adducts that modify DNA. Aflatoxin B1 induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. This transversion is common in hepatocellular carcinoma patients living in regions with high levels of aflatoxin contamination. Aflatoxin B2 is the dihydro derivative of aflatoxin B1, a naturally occuring mycotoxin and food contaminant that is a likely pathogen that causes hepatocellular carcinoma.[Cayman Chemical]

Definition

ChEBI: An aflatoxin having a hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.

General Description

Aflatoxin B2 is one of the fungal metabolic products produced in food and feed, contaminated by?Aspergillus?species.

Safety Profile

Confirmed human carcinogen with experimental tumorigenic data. Poison by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes. See also various aflatoxins.

Potential Exposure

Aflatoxins are a group of toxic metabolites produced by certain types of fungi. Aflatoxins are not commercially manufactured; they are naturally occurring contaminants that are formed by fungi on food during conditions of high temperatures and high humidity. Most human exposure to aflatoxins occurs through ingestion of contaminated food. The estimated amount of aflatoxins that Americans consume daily is estimated to be 0.15 0.50 μg. Grains, peanuts, tree nuts, and cottonseed meal are among the more common foods on which these fungi grow. Meat, eggs, milk, and other edible products from animals that consume aflatoxincontaminated feed may also contain aflatoxins. Aflatoxins can also be breathed in

Shipping

UN3172 Toxins, extracted from living sources, solid or liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Use of oxidizing agents, such as hydrogen peroxide or 5% sodium hypochlorite bleach. Acids and bases may also be used.

AFLATOXIN B2 Preparation Products And Raw materials

Raw materials

Preparation Products

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AFLATOXIN B2 Suppliers

Nanjing Shizhou Biology Technology Co.,Ltd
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View Lastest Price from AFLATOXIN B2 manufacturers

Hebei Fengjia New Material Co., Ltd
Product
AFLATOXIN B2 7220-81-7
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000
Release date
2024-09-02
Hebei Weibang Biotechnology Co., Ltd
Product
AFLATOXIN B2 7220-81-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-08-06
Hebei Mojin Biotechnology Co., Ltd
Product
AFLATOXIN B2 7220-81-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-30

7220-81-7, AFLATOXIN B2Related Search:


  • AFLATOXIN B2
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  • ,9,9a-alpha-hexahydro-4-methoxy-
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  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxy-
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  • dihydroaflatoxinb1
  • 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione
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  • 4-Methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-H]chromene-1,11-dione
  • 9aalpha-hexahydro-4-methoxy-
  • cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a-alpha,8
  • cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6aalpha,8,
  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR-cis)-
  • (6aR)-2,3,6aα,8,9,9aα-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
  • (6aR,9aS)-2,3,6a,8,9,9a-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
  • Aflatoxine B2
  • Aflatoxin B2 Dihydroaflatoxine B1
  • (6aR,9aS)-4-methoxy-2,3,9,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11(6aH,8H)-dione
  • Aflatoxin B2, 98%, from Aspergillus flavus
  • AflatoxinB2Solution,3mg/L
  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR,9aS)-
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  • AFLATOXIN B2(RG) 10mg
  • 7220-81-7
  • C17H14O6
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