Lythranidine 12-acetate

Product Name
Lythranidine 12-acetate
CAS No.
32420-54-5
Chemical Name
Lythranidine 12-acetate
Synonyms
Lythranine;Lythranidine 12-acetate
CBNumber
CB02408350
Molecular Formula
C28H37NO5
Formula Weight
467.59708
MOL File
32420-54-5.mol
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Hazard and Precautionary Statements (GHS)

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Lythranidine 12-acetate Chemical Properties,Usage,Production

Description

A non-crystallizable alkaloid isolated from Lythrum anceps Mak., the base yields a very hygroscopic hydrochloride and the O,O-diacetate, the latter giving a crystalline hydrochloride, m.p. 180-218°C (dec.); [α]25D - 33°. When hydrolyzedwith dilute alkalies, the alkaloid gives Lythranidine (q.v.) while treatment with formaldehyde yields Lythamine. Dehydrogenation with Pd-C followed by oxidiation with KMn04 furnishes dipicolinic acid.

References

Fujita et ai., Tetrahedron Lett., 4595 (1967) Fujita, Fuji, Tanaka., ibid, 5905 (1968) Fujita et ai., Chern. Pharrn. Bull., 18, 2216 (1970) Fujita, Fuji, Tanaka.,J. Chern. Soc., C, 205 (1971) Fujita, Fuji., ibid, 1651 (1971)

Lythranidine 12-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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