ChemicalBook > CAS DataBase List > 7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE

7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE

Product Name
7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE
CAS No.
6529-94-8
Chemical Name
7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE
Synonyms
7-methoxy-4H-1,4-benzoxazin-3-one;7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE;2H-1,4-Benzoxazin-3(4H)-one, 7-methoxy-;7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one;7-Methoxy-3,4-dihydro-2H-1,4-benzoxazin-3-one
CBNumber
CB02448488
Molecular Formula
C9H9NO3
Formula Weight
179.17
MOL File
6529-94-8.mol
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7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE Property

Melting point:
158-160 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point:
374.0±42.0 °C(Predicted)
Density 
1.245±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.12±0.20(Predicted)
Appearance
Brown to black Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M916053
Product name
7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
M916053
Product name
7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one
Packaging
50mg
Price
$130
Updated
2021/12/16
TRC
Product number
M916053
Product name
7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one
Packaging
100mg
Price
$200
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0151403
Product name
7-METHOXY-2H-BENZO(B)(1,4)OXAZIN-3(4H)-ONE
Purity
95.00%
Packaging
5MG
Price
$505.49
Updated
2021/12/16
Chemenu
Product number
CM123229
Product name
7-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one
Purity
97%
Packaging
1g
Price
$327
Updated
2021/12/16
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7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE Chemical Properties,Usage,Production

Synthesis

1268818-19-4

6529-94-8

GENERAL METHOD: 2a (2 mmol) was dissolved in acetic acid (10 mL) and powdered iron (12 mmol) was added with stirring. The reaction mixture was heated to reflux for 2 hours, during which time the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove acetic acid. Ethyl acetate (EtOAc, 20 mL) was added, stirred for 2 min and filtered to remove iron impurities. The insoluble iron residue was washed with ethyl acetate (20 mL). The filtrate and washings were combined and dried with anhydrous magnesium sulfate (MgSO4). The solvent was removed by concentration under reduced pressure and the resulting crude product was purified by column chromatography to give the pure product 3a.

References

[1] Tetrahedron, 2011, vol. 67, # 6, p. 1187 - 1192
[2] European Journal of Medicinal Chemistry, 2017, vol. 132, p. 90 - 107

7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE Suppliers

China 37 India 1 United States 2 Global 40
A.J Chemicals
Tel
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Fax
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
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6529-94-8, 7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONERelated Search:

Dibenzothiophene Aniline Thianaphthene Benzothiazole 7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE 7-Methoxy-3,4-dihydro-2H-benzo[1,4]oxazine 2,4-Dihydroxy-7-methoxy-2H,1,4-benzoxazin-3(4H)one 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL

  • 7-METHOXY-2H-1,4-BENZOXAZIN-3(4H)-ONE
  • 7-Methoxy-3,4-dihydro-2H-1,4-benzoxazin-3-one
  • 7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one
  • 2H-1,4-Benzoxazin-3(4H)-one, 7-methoxy-
  • 7-methoxy-4H-1,4-benzoxazin-3-one
  • 6529-94-8