ChemicalBook > CAS DataBase List > 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE

Product Name: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE
CAS No.: 131084-55-4
Chemical Name: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE
Synonyms: 100186;5-Chloro-6-azaindole;5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE;1H-PYRROLO[3,2-C]PYRIDIN,5-CHLORO-;1H-Pyrrolo[2,3-c]pyridine, 5-chloro-
CBNumber: CB02452429
Molecular Formula: C7H5ClN2
Formula Weight: 152.58
MOL File: 131084-55-4.mol

Less

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Property

Boiling point:: 335.8±22.0 °C(Predicted)
Density: 1.425
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 13.75±0.40(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C7H5ClN2/c8-7-3-5-1-2-9-6(5)4-10-7/h1-4,9H
InChIKey: XAIYMAHUJMVDHR-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC2C=CNC1=2
CAS DataBase Reference: 131084-55-4

Less

Safety

HS Code: 2933998090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: C422190
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 500mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: X9786
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 1g
Price: $91
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43579
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43579
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 500mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43579
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Less

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Chemical Properties,Usage,Production

Uses

5-Chloro-1H-pyrrolo[2,3-c]pyridine is a versatile building block in chemical synthesis, commonly utilized in the pharmaceutical and agrochemical industries for the production of various biologically active compounds.

Synthesis

142078-36-2

131084-55-4

Using 2-(2-chloro-5-nitropyridin-4-yl)-N,N-dimethylvinyl-1-amine (221.2, 1.0 g, 4.4 mmol, 1.0 eq.) as starting material, it was dissolved in acetic acid (10 mL) at room temperature. Subsequently, iron powder (1.2 g, 22.0 mmol, 5.0 eq.) was added to this solution. The reaction mixture was heated to 90 °C and the reaction was stirred at this temperature for 2 hours. Upon completion of the reaction, sodium carbonate solution was slowly added to the reaction mixture to neutralize the reaction system, followed by extraction with ethyl acetate. All organic layers were combined, washed with brine solution to remove water-soluble impurities, and then the organic phase was dried with anhydrous sodium sulfate. After drying, the solvent was removed by concentration under reduced pressure to give the crude product. The crude product was further purified by column chromatography using a hexane solution of 30% ethyl acetate as eluent to give the target compound 5-chloro-1H-pyrrolo[2,3-c]pyridine (221.3, 0.65 g, 96.98% yield). Mass spectrometry (electrospray ionization): m/z 153.47 [M + H]+.

References

[1] Patent: WO2018/71794, 2018, A1. Location in patent: Paragraph 001020; 001022
[2] Patent: WO2010/42337, 2010, A1. Location in patent: Page/Page column 42; 43

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Suppliers

China 155 India 4 Switzerland 2 United Kingdom 2 United States 10 Global 173

Wuxi KaideRui Pharmaceutical Technology Co., Ltd

Tel: 19906241957
Fax: -
Email: 1557216087@qq.com
Country: China
ProdList: 1837
Advantage: 55

Shanghai yuanzuo medical technology co., LTD

Tel: 021-31775309; 15221510662
Email: yi_shiyan@yuanzuopharm.com
Country: China
ProdList: 139
Advantage: 58

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Suzhou Sibian Chemical Technology Co.,Ltd.

Tel: 0512-65617459 18915409046
Fax: 0512-65617459
Email: sales@sibian-chem.com
Country: China
ProdList: 1922
Advantage: 55

Shijiazhuang suchen Chemical Technology Co. LTD

Tel: 186-33933494 18032288352
Fax: 0311-85310887
Email: 1130239@qq.com
Country: China
ProdList: 202
Advantage: 60

Accendatech Co., LTD.

Tel: 13132578992
Fax: 022-83718543-802
Email: sales@accendatech.com
Country: China
ProdList: 332
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Runpharm Technology Limited

Tel: 18171398856 2968382473
Fax: 0086-21-50758330
Email: service@runpharm.com
Country: China
ProdList: 716
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1876
Advantage: 55

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2647
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Shanghai YuYuan Pharmaceutical Co., Ltd.

Tel: 13052276172
Fax: 13052276172
Email: product@yuyuanpharm.com
Country: China
ProdList: 493
Advantage: 55

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Jiaxing Novartis Chemical Co., Ltd.

Tel: 18957373295
Fax: -
Country: China
ProdList: 1580
Advantage: 58

ShangHai Yuchuan Pharmaceutical Technology Co., Ltd.

Tel: 02161555100
Fax: -
Country: China
ProdList: 820
Advantage: 58

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Shenzhen Gre-syn Chemical Technology Co., Ltd.

Tel: 0755-0755-89366401 18617066401
Fax: -
Email: hangbingfang@163.com
Country: China
ProdList: 952
Advantage: 55

AN PharmaTech Co Ltd

Tel: 86(21)68097365
Fax: 86(21)33321566
Email: sales@anpharma.net
Country: China
ProdList: 4891
Advantage: 55

Xi'an NewProChem Co.,Ltd.

Tel: 15332490153
Fax: QQ 2725398181
Email: newprochem@126.com
Country: China
ProdList: 991
Advantage: 55

Bellen Chemistry Co., Ltd.

Tel: 010-60400365-8001 15910885229
Fax: 010-60400361
Email: service@bellenchem.com
Country: China
ProdList: 4514
Advantage: 60

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Chengdu J&B Technology Co., Ltd.

Tel: 028-61186694 15608078506
Fax: 028-61186694
Email: 609128801@qq.com
Country: China
ProdList: 837
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Chemspon Bio-Tech Co., Ltd

Tel: 0571-88937695 88937835 13606537248
Email: sales@chemspon.com
Country: China
ProdList: 249
Advantage: 58

Shanghai Brain Biotechnology Co., Ltd.

Tel: 13564638271
Fax: 021-68948280
Email: shhjiang1977@163.com
Country: China
ProdList: 2987
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Suzhou JingTong Pharmaceutical Co., Ltd.

Tel: 13675155016
Fax: 18912765016
Email: tongtf110@sina.com
Country: China
ProdList: 963
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9125
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12475
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Less

View Lastest Price from 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE manufacturers

Career Henan Chemical Co

Product: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE 131084-55-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-06-21

131084-55-4, 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINERelated Search:

6-Chloro-1,3-dihydro-2H-pyrrolo[3,2-c]pyridin-2-one 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 5-CHLORO-1,3-DIHYDRO-2H-PYRROLO[3,2-B] PYRIDIN-2-ONE 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 5-chloro- 5-CHLORO (1H)INDAZOLE 5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine 5-Chloro-6-azaindole-3-carboxaldehyde 5-Chloro-1H-pyrazolo[4,3-b]pyridine 5-Chloro-1,2,3,4-tetrahydroisoquinoline 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE 5-Chloro-[1,2,4]triazolo[1,5-a]pyridine 5-CHLORO-3-HYDROXY (1H)INDAZOLE 5-CHLORO-1H-INDOL-3-METHYLAMINE 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid 5-Chloro-1,3,4-thiadiazol-2-ylamine 6-Chloro-3H-1,2,3-triazolo[4,5-c]pyridine 5-Chloro-7-azaindole-3-carboxaldehyde 5-Chloro-7-azaindole-3-carboxylic acid Methyl ester

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE

5-Chloro-6-azaindole

1H-Pyrrolo[2,3-c]pyridine, 5-chloro-

1H-PYRROLO[3,2-C]PYRIDIN,5-CHLORO-

100186

131084-55-4

131085-55-4

Heterocycle-Pyridine series