(3-CHLOROPYRIDIN-2-YL)METHANOL

Product Name: (3-CHLOROPYRIDIN-2-YL)METHANOL
CAS No.: 60588-81-0
Chemical Name: (3-CHLOROPYRIDIN-2-YL)METHANOL
Synonyms: 3-Chloropyridine-2-methanol;3-Chloro-2-pyridineMethanol;(3-Chloro-2-pyridyl)methanol;2-Pyridinemethanol, 3-chloro-;(3-CHLOROPYRIDIN-2-YL)METHANOL;3-Chloro-2-hydroxymethylpyridine;(3-Chloropyridin-2-yl)methanol 95+%
CBNumber: CB02456038
Molecular Formula: C6H6ClNO
Formula Weight: 143.57
MOL File: 60588-81-0.mol

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(3-CHLOROPYRIDIN-2-YL)METHANOL Property

Boiling point:: 234.9±25.0 °C(Predicted)
Density: 1.324±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 12.80±0.10(Predicted)
form: powder
color: Yellow

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Safety

HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: C381633
Product name: (3-Chloropyridin-2-yl)methanol
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 056385
Product name: (3-Chloropyridin-2-yl)methanol
Purity: >95%
Packaging: 5g
Price: $807
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141108
Product name: (3-Chloropyridin-2-yl)methanol
Packaging: 5G
Price: $850
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 35995
Product name: (3-Chloropyridin-2-yl)methanol
Purity: 95+%
Packaging: 5G
Price: $900
Updated: 2021/12/16

AK Scientific

Product number: Z4931
Product name: (3-Chloropyridin-2-yl)methanol
Packaging: 10g
Price: $961
Updated: 2021/12/16

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(3-CHLOROPYRIDIN-2-YL)METHANOL Chemical Properties,Usage,Production

Synthesis

57266-69-0

60588-81-0

The general procedure for the synthesis of 3-chloro-2-pyridinemethanol from 3-chloro-2-pyridinecarboxylic acid is as follows: to a solution of tetrahydrofuran (THF, 40 mL) containing 3-chloro-2-pyridinecarboxylic acid (2.1 g, 13.33 mmol, 1.00 eq.) was added sequentially triethylamine (Et3N, 2.7 g, 26.68 mmol, 2.00 eq.) and chloroformic acid isopropyl chloroformate (2.45 g, 19.99 mmol, 1.50 eq.) were stirred and added dropwise at 0 °C. The reaction mixture was continued to be stirred at room temperature for 1 hour. After completion of the reaction, the solid impurities were removed by filtration. Sodium borohydride (NaBH4, 1.53 g, 40.44 mmol, 3.00 equiv) was added to the filtrate and the resulting solution was stirred at room temperature for 2 hours. The reaction mixture was diluted with 50 mL of water and extracted with ethyl acetate (EtOAc, 2 x 100 mL). The organic layers were combined, washed with 50 mL of saturated sodium chloride (NaCl) solution, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent of ethyl acetate/petroleum ether (1:6) to give 0.9 g (47% yield) of 3-chloropyridine-2-methanol as a colorless oil.

References

[1] Patent: US2018/162822, 2018, A1. Location in patent: Paragraph 0606
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 11, p. 1827 - 1837

(3-CHLOROPYRIDIN-2-YL)METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(3-CHLOROPYRIDIN-2-YL)METHANOL Suppliers

China 73 India 1 United Kingdom 2 United States 7 Global 83

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View Lastest Price from (3-CHLOROPYRIDIN-2-YL)METHANOL manufacturers

Career Henan Chemical Co

Product: (3-CHLOROPYRIDIN-2-YL)METHANOL 60588-81-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1lg; 2kg; 5kg; 10kg; 100kg
Release date: 2019-08-31

60588-81-0, (3-CHLOROPYRIDIN-2-YL)METHANOLRelated Search:

CLOPYRALID METHYL ESTER Picloram Clopyralid Tetrachloropyridine-2-carboxylic acid 3,4,5-Trichloropyridine-2-carboxylic acid PICLORAM METHYL ESTER METHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE ETHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE 3,5,6-TRICHLORO-4-HYDRAZINO-PYRIDINE-2-CARBOXYLIC ACID 2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-1H-ISOINDOLE-1,3(2H)-DIONE N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)UREA METHYL 3,4,5-TRICHLOROPYRIDINE-2-CARBOXYLATE N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-(([(2,4-DICHLOROBENZYL)OXY]IMINO)METHYL)UREA [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHANOL N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-[(METHOXYIMINO)METHYL]UREA 3-CHLORO-5-(TRIFLUOROMETHYL)-2-([3-(TRIFLUOROMETHYL)PHENOXY]METHYL)PYRIDINE [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHYL N-[3-(TRIFLUOROMETHYL)PHENYL]CARBAMATE ISOBUTYL 4-AMINO-3,5,6-TRICHLOROPYRIDINE-2-CARBOXYLATE

(3-CHLOROPYRIDIN-2-YL)METHANOL

3-Chloro-2-pyridineMethanol

3-Chloro-2-hydroxymethylpyridine

3-Chloropyridine-2-methanol

(3-Chloro-2-pyridyl)methanol

(3-Chloropyridin-2-yl)methanol 95+%

2-Pyridinemethanol, 3-chloro-

60588-81-0