ChemicalBook > CAS DataBase List > (3-CHLOROPYRIDIN-2-YL)METHANOL

(3-CHLOROPYRIDIN-2-YL)METHANOL

Product Name
(3-CHLOROPYRIDIN-2-YL)METHANOL
CAS No.
60588-81-0
Chemical Name
(3-CHLOROPYRIDIN-2-YL)METHANOL
Synonyms
3-Chloropyridine-2-methanol;3-Chloro-2-pyridineMethanol;(3-Chloro-2-pyridyl)methanol;2-Pyridinemethanol, 3-chloro-;(3-CHLOROPYRIDIN-2-YL)METHANOL;3-Chloro-2-hydroxymethylpyridine;(3-Chloropyridin-2-yl)methanol 95+%
CBNumber
CB02456038
Molecular Formula
C6H6ClNO
Formula Weight
143.57
MOL File
60588-81-0.mol
More
Less

(3-CHLOROPYRIDIN-2-YL)METHANOL Property

Boiling point:
234.9±25.0 °C(Predicted)
Density 
1.324±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
12.80±0.10(Predicted)
form 
powder
color 
Yellow
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C381633
Product name
(3-Chloropyridin-2-yl)methanol
Packaging
100mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
056385
Product name
(3-Chloropyridin-2-yl)methanol
Purity
>95%
Packaging
5g
Price
$807
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC141108
Product name
(3-Chloropyridin-2-yl)methanol
Packaging
5G
Price
$850
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
35995
Product name
(3-Chloropyridin-2-yl)methanol
Purity
95+%
Packaging
5G
Price
$900
Updated
2021/12/16
AK Scientific
Product number
Z4931
Product name
(3-Chloropyridin-2-yl)methanol
Packaging
10g
Price
$961
Updated
2021/12/16
More
Less

(3-CHLOROPYRIDIN-2-YL)METHANOL Chemical Properties,Usage,Production

Synthesis

57266-69-0

60588-81-0

The general procedure for the synthesis of 3-chloro-2-pyridinemethanol from 3-chloro-2-pyridinecarboxylic acid is as follows: to a solution of tetrahydrofuran (THF, 40 mL) containing 3-chloro-2-pyridinecarboxylic acid (2.1 g, 13.33 mmol, 1.00 eq.) was added sequentially triethylamine (Et3N, 2.7 g, 26.68 mmol, 2.00 eq.) and chloroformic acid isopropyl chloroformate (2.45 g, 19.99 mmol, 1.50 eq.) were stirred and added dropwise at 0 °C. The reaction mixture was continued to be stirred at room temperature for 1 hour. After completion of the reaction, the solid impurities were removed by filtration. Sodium borohydride (NaBH4, 1.53 g, 40.44 mmol, 3.00 equiv) was added to the filtrate and the resulting solution was stirred at room temperature for 2 hours. The reaction mixture was diluted with 50 mL of water and extracted with ethyl acetate (EtOAc, 2 x 100 mL). The organic layers were combined, washed with 50 mL of saturated sodium chloride (NaCl) solution, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent of ethyl acetate/petroleum ether (1:6) to give 0.9 g (47% yield) of 3-chloropyridine-2-methanol as a colorless oil.

References

[1] Patent: US2018/162822, 2018, A1. Location in patent: Paragraph 0606
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 11, p. 1827 - 1837

(3-CHLOROPYRIDIN-2-YL)METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(3-CHLOROPYRIDIN-2-YL)METHANOL Suppliers

China 73 India 1 United Kingdom 2 United States 7 Global 83
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
More
Less

View Lastest Price from (3-CHLOROPYRIDIN-2-YL)METHANOL manufacturers

Career Henan Chemical Co
Product
(3-CHLOROPYRIDIN-2-YL)METHANOL 60588-81-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

60588-81-0, (3-CHLOROPYRIDIN-2-YL)METHANOLRelated Search:

CLOPYRALID METHYL ESTER Picloram Clopyralid Tetrachloropyridine-2-carboxylic acid 3,4,5-Trichloropyridine-2-carboxylic acid PICLORAM METHYL ESTER METHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE ETHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE 3,5,6-TRICHLORO-4-HYDRAZINO-PYRIDINE-2-CARBOXYLIC ACID 2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-1H-ISOINDOLE-1,3(2H)-DIONE N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)UREA METHYL 3,4,5-TRICHLOROPYRIDINE-2-CARBOXYLATE N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-(([(2,4-DICHLOROBENZYL)OXY]IMINO)METHYL)UREA [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHANOL N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-[(METHOXYIMINO)METHYL]UREA 3-CHLORO-5-(TRIFLUOROMETHYL)-2-([3-(TRIFLUOROMETHYL)PHENOXY]METHYL)PYRIDINE [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHYL N-[3-(TRIFLUOROMETHYL)PHENYL]CARBAMATE ISOBUTYL 4-AMINO-3,5,6-TRICHLOROPYRIDINE-2-CARBOXYLATE

  • (3-CHLOROPYRIDIN-2-YL)METHANOL
  • 3-Chloro-2-pyridineMethanol
  • 3-Chloro-2-hydroxymethylpyridine
  • 3-Chloropyridine-2-methanol
  • (3-Chloro-2-pyridyl)methanol
  • (3-Chloropyridin-2-yl)methanol 95+%
  • 2-Pyridinemethanol, 3-chloro-
  • 60588-81-0