ChemicalBook > CAS DataBase List > (17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID

(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID

Product Name
(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID
CAS No.
183509-24-2
Chemical Name
(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID
Synonyms
17(R)-HETE;OPPIPPRXLIDJKN-DWUYYRGZSA-N;17(R)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid;(17R,5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid;(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID;5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (5Z,8Z,11Z,14Z,17R)-
CBNumber
CB02456371
Molecular Formula
C20H32O3
Formula Weight
320.47
MOL File
183509-24-2.mol
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(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID Property

Boiling point:
477.3±33.0 °C(Predicted)
Density 
0.984±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
pka
4.75±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010637
Product name
17(R)-HETE
Purity
≥98%
Packaging
25μg
Price
$146
Updated
2024/03/01
Cayman Chemical
Product number
10010637
Product name
17(R)-HETE
Purity
≥98%
Packaging
50μg
Price
$278
Updated
2024/03/01
Cayman Chemical
Product number
10010637
Product name
17(R)-HETE
Purity
≥98%
Packaging
100μg
Price
$525
Updated
2024/03/01
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(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID Chemical Properties,Usage,Production

Description

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. 17(R)-HETE is an inactive isomer of 17-HETE, whereas the (S) enantiomer can inhibit proximal tubule ATPase activity at a concentration of 2 μM. 1

References

1. Carroll, M.A., Balazy, M., Margiotta, P., et al. Cytochrome P-450-dependent HETEs: Profile of biological activity and stimulation by vasoactive peptides Am. J. Physiol. 271(4 Pt 2),R863-R869(1996).

(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID Suppliers

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183509-24-2, (17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACIDRelated Search:

(17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID

  • (17R,5Z,8Z,11Z,14Z)-17-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID
  • 17(R)-HETE
  • OPPIPPRXLIDJKN-DWUYYRGZSA-N
  • (17R,5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid
  • 17(R)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid
  • 5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (5Z,8Z,11Z,14Z,17R)-
  • 183509-24-2