ChemicalBook > CAS DataBase List > COMPOUND 401
COMPOUND 401
- Product Name
- COMPOUND 401
- CAS No.
- 168425-64-7
- Chemical Name
- COMPOUND 401
- Synonyms
- CS-315;Morpholino a;Compound 401, >=98%;COMPOUND401;COMPOUND-401;Compound 401, 10 mM in DMSO;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one>2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one;4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-
- CBNumber
- CB02458229
- Molecular Formula
- C16H15N3O2
- Formula Weight
- 281.31
- MOL File
- 168425-64-7.mol
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COMPOUND 401 Property
- Melting point:
- 184-186℃ (ethanol )
- Boiling point:
- 456.9±55.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Store at RT
- solubility
- DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming)
- pka
- 1.01±0.20(Predicted)
- form
- powder to crystal
- color
- White to Light yellow
- CAS DataBase Reference
- 168425-64-7
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Safety
- HS Code
- 2934.99.4400
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- M2537
- Product name
- 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
- Purity
- >98.0%(GC)
- Packaging
- 10mg
- Price
- $83
- Updated
- 2024/03/01
TCI Chemical
- Product number
- M2537
- Product name
- 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
- Purity
- >98.0%(GC)
- Packaging
- 50mg
- Price
- $292
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21769
- Product name
- Compound 401
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21769
- Product name
- Compound 401
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21769
- Product name
- Compound 401
- Packaging
- 10mg
- Price
- $153
- Updated
- 2024/03/01
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COMPOUND 401 Chemical Properties,Usage,Production
Uses
Compound 401 is a selective inhibitor of DNA-PK and FRAP.
Biological Activity
Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC 50 values are 0.28 and 5.3 μ M respectively). Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC 50 values are all > 100 μ M). Induces apoptosis in vitro .
COMPOUND 401 Preparation Products And Raw materials
Raw materials
Preparation Products
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COMPOUND 401 Suppliers
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