8-METHYL-2,4-DICHLOROQUINAZOLINE

Product Name: 8-METHYL-2,4-DICHLOROQUINAZOLINE
CAS No.: 39576-83-5
Chemical Name: 8-METHYL-2,4-DICHLOROQUINAZOLINE
Synonyms: 8-METHYL-2,4-DICHLOROQUINAZOLINE;2,4-DICHLORO-8-METHYLQUINAZOLINE;Quinazoline, 2,4-dichloro-8-methyl-
CBNumber: CB02465650
Molecular Formula: C9H6Cl2N2
Formula Weight: 213.06
MOL File: 39576-83-5.mol

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8-METHYL-2,4-DICHLOROQUINAZOLINE Property

Boiling point:: 292℃
Density: 1.418
Flash point:: 158℃
storage temp.: Inert atmosphere,Room Temperature
pka: -0.20±0.30(Predicted)
Appearance: White to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 118759
Product name: 2,4-Dichloro-8-methylquinazoline
Purity: >97%
Packaging: 500mg
Price: $429
Updated: 2021/12/16

Matrix Scientific

Product number: 118759
Product name: 2,4-Dichloro-8-methylquinazoline
Purity: >97%
Packaging: 1g
Price: $579
Updated: 2021/12/16

AK Scientific

Product number: Y6210
Product name: 2,4-Dichloro-8-methylquinazoline
Packaging: 1g
Price: $253
Updated: 2021/12/16

Chemenu

Product number: CM121433
Product name: 2,4-Dichloro-8-methylquinazoline
Purity: 95%
Packaging: 5g
Price: $421
Updated: 2021/12/16

ACHEMBLOCK

Product number: P38338
Product name: 2,4-Dichloro-8-methylquinazoline
Purity: 95%
Packaging: 5G
Price: $635
Updated: 2021/12/16

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8-METHYL-2,4-DICHLOROQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

67449-23-4

39576-83-5

The general procedure for the synthesis of 2,4-dichloro-8-methylquinazoline from 2,4-dihydroxy-8-methylquinazoline was as follows: 8-methylquinazoline-2,4(1H,3H)-dione (4.50 g, 25.50 mmol) was added to phosphorochloridic acid (47.6 mL, 510.9 mmol). The reaction mixture was stirred at 100 °C for 6 h and subsequently cooled to room temperature. The reaction solution was slowly poured into water (300 mL) and the internal temperature was controlled to be below 60°C. After precipitating the solid, the product was collected by filtration to afford 2,4-dichloro-8-methylquinazoline (4.30 g, 79% yield).

References

[1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 3, p. 254 - 259
[2] Patent: US5064833, 1991, A
[3] Patent: EP322133, 1991, B1
[4] Patent: EP322133, 1989, A1
[5] Synthesis (Germany), 2016, vol. 48, # 8, p. 1226 - 1234

8-METHYL-2,4-DICHLOROQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-METHYL-2,4-DICHLOROQUINAZOLINE Suppliers

China 57 India 1 United States 5 Global 63

Chiba Pharmaceutical Science and technology Co, Ltd.

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View Lastest Price from 8-METHYL-2,4-DICHLOROQUINAZOLINE manufacturers

Career Henan Chemical Co

Product: 2,4-dichloro-8-methylquinazoline 39576-83-5
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-09

39576-83-5, 8-METHYL-2,4-DICHLOROQUINAZOLINERelated Search:

Chlorotrimethylsilane Dichloroethane CHLOROETHANE Xylene 2,4-dichloro-8-(trifluoromethoxy)quinazoline 2,4-DICHLORO-7-BROMOQUINAZOLINE 2,4-DICHLORO-1,2,3,4-TETRAHYDRO-7-METHYLQUINAZOLINE 2,4-Dichloroquinazoline

2,4-DICHLORO-8-METHYLQUINAZOLINE

8-METHYL-2,4-DICHLOROQUINAZOLINE

Quinazoline, 2,4-dichloro-8-methyl-

39576-83-5