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1-bromo-4-phenylbutan-2-one

Product Name
1-bromo-4-phenylbutan-2-one
CAS No.
31984-10-8
Chemical Name
1-bromo-4-phenylbutan-2-one
Synonyms
1-bromo-4-phenylbutan-2-one;1-Bromo-4-phenyl-2-Butanone;2-Butanone, 1-bromo-4-phenyl-;5-Piperazinecarboxamide,N,N-dimethyl-;2-Thiopheneaceticacid,10-bromo-α-oxo-,ethylester
CBNumber
CB02473806
Molecular Formula
C10H11BrO
Formula Weight
227.1
MOL File
31984-10-8.mol
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1-bromo-4-phenylbutan-2-one Property

Melting point:
47-49 °C
Boiling point:
290.1±15.0 °C(Predicted)
Density 
1.371±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to off-white Solid
InChI
InChI=1S/C10H11BrO/c11-8-10(12)7-6-9-4-2-1-3-5-9/h1-5H,6-8H2
InChIKey
APAZZDBYJISGLX-UHFFFAOYSA-N
SMILES
C(Br)C(=O)CCC1=CC=CC=C1
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Safety

HS Code 
2914790090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B293070
Product name
1-Bromo-4-phenylbutan-2-one
Packaging
250mg
Price
$310
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB146822
Product name
1-Bromo-4-phenyl-2-butanone
Packaging
1g
Price
$390
Updated
2021/12/16
Matrix Scientific
Product number
125519
Product name
1-Bromo-4-phenylbutan-2-one
Purity
97%
Packaging
5g
Price
$448
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB146822
Product name
1-Bromo-4-phenyl-2-butanone
Packaging
50mg
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB146822
Product name
1-Bromo-4-phenyl-2-butanone
Packaging
100mg
Price
$86
Updated
2021/12/16
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1-bromo-4-phenylbutan-2-one Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 5140, 1985 DOI: 10.1021/jo00225a032

Synthesis

2550-26-7

31984-10-8

General procedure for the synthesis of 1-bromo-4-phenylbutan-2-one from benzylacetone: Bromine (19 mL, 1.1 mmol) was slowly added to a stirred solution of 4-phenylbutan-2-one (50 g, 1 mmol) in methanol (350 mL) at 0 °C. The reaction mixture was stirred continuously at 15°C for 4 hours. Upon completion of the reaction, the reaction mixture was diluted with water (500 mL) and extracted with dichloromethane (2 x 500 mL). The organic layers were combined, washed with brine solution, dried over anhydrous Na2SO4 and concentrated under reduced pressure. The residue was dissolved in petroleum ether and crystallized in a refrigerator for 5 hours. The solid was collected by filtration to afford the target product 1-bromo-4-phenylbutan-2-one (72 g, 93.98%) as a white solid.1H NMR (300 MHz, CDCl3): δ 2.9 (q, 4H), 3.8 (s, 2H), 7.2 (m, 3H), 7.3 (m, 2H).13C NMR (100 MHz, CDCl3): δ 29.87,34.24,41.38,126.34 (2c), 128.28 (2c), 128.57,140.29,201.18.

References

[1] Journal of Chemical Sciences, 2015, vol. 127, # 11, p. 2023 - 2028
[2] Patent: KR2017/25682, 2017, A. Location in patent: Paragraph 0093; 0094-0097
[3] Patent: US2003/149294, 2003, A1
[4] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 9, p. 3225 - 3234
[5] Synthetic Communications, 2012, vol. 42, # 9, p. 1288 - 1305

1-bromo-4-phenylbutan-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-bromo-4-phenylbutan-2-one Suppliers

China 62 India 7 Switzerland 1 United Kingdom 1 United States 6 Global 77
Achemica
Tel
--
Fax
--
Email
contact@achemica.com
Country
Switzerland
ProdList
6155
Advantage
50
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View Lastest Price from 1-bromo-4-phenylbutan-2-one manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-Bromo-4-phenyl-2-butanone 31984-10-8
Price
US $1.10-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-23
Career Henan Chemical Co
Product
1-Bromo-4-phenyl-2-Butanone 31984-10-8
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-02-18

31984-10-8, 1-bromo-4-phenylbutan-2-oneRelated Search:

Methanol Sodium Sodium metabisulfite

  • 1-Bromo-4-phenyl-2-Butanone
  • 2-Butanone, 1-bromo-4-phenyl-
  • 5-Piperazinecarboxamide,N,N-dimethyl-
  • 2-Thiopheneaceticacid,10-bromo-α-oxo-,ethylester
  • 1-bromo-4-phenylbutan-2-one
  • 31984-10-8