ChemicalBook > CAS DataBase List > (S)-N-Fmoc-2-(2'-propylenyl)alanine

(S)-N-Fmoc-2-(2'-propylenyl)alanine

Product Name
(S)-N-Fmoc-2-(2'-propylenyl)alanine
CAS No.
288617-71-0
Chemical Name
(S)-N-Fmoc-2-(2'-propylenyl)alanine
Synonyms
FMoc-α-Me-Gly(Allyl)-OH;Fmoc-alpha-All-D-Ala-OH;Fmoc-α-Me-Gly(Allyl)-OH;(S)-N-FMOC-Α-ALLYLALANINE;(S)-N-Fmoc-A-Allylalanine;(S)-N-Fmoc-alpha-allylalanine;Fmoc-(S)-2-(2-propenyl)Ala-OH;Fmoc-(S)-2-(2-propenyl)alanine;(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-alpha-methyl-L-allylglycine
CBNumber
CB02485702
Molecular Formula
C21H21NO4
Formula Weight
351.4
MOL File
288617-71-0.mol
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(S)-N-Fmoc-2-(2'-propylenyl)alanine Property

Boiling point:
564.3±45.0 °C(Predicted)
Density 
1.224
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
liquid
pka
3.81±0.11(Predicted)
color 
pale yellow
InChIKey
FNCSRFHDUZYOCR-NRFANRHFSA-N
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Safety

Hazard Codes 
N
Risk Statements 
50
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
TSCA 
No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

TRC
Product number
H950188
Product name
(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylpent-4-enoicacid
Packaging
50mg
Price
$100
Updated
2021/12/16
Usbiological
Product number
278035
Product name
Fmoc-alpha-methyl-L-allylglycine
Packaging
25mg
Price
$333
Updated
2021/12/16
Activate Scientific
Product number
AS46299
Product name
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpent-4-enoic acid
Purity
97% ee
Packaging
1g
Price
$383
Updated
2021/12/16
Chem-Impex
Product number
29359
Product name
Fmoc-α-methyl-L-allylglycine,≥99%(HPLC)
Purity
≥99%(HPLC)
Packaging
1G
Price
$483.39
Updated
2021/12/16
ChemPep
Product number
180765
Product name
Fmoc-α-Me-Gly(Allyl)-OH
Packaging
1g
Price
$500
Updated
2021/12/16
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(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemical Properties,Usage,Production

Uses

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

(S)-N-Fmoc-2-(2'-propylenyl)alanine Preparation Products And Raw materials

Raw materials

Preparation Products

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288617-71-0, (S)-N-Fmoc-2-(2'-propylenyl)alanineRelated Search:


  • (S)-N-Fmoc-2-(2'-propylenyl)alanine
  • (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
  • (S)-N-Fmoc-alpha-allylalanine
  • (S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine
  • Fmoc-alpha-methyl-L-allylglycine
  • (S)-N-FMOC-Α-ALLYLALANINE
  • FMoc-α-Me-Gly(Allyl)-OH
  • (S)-N-Fmoc-α-2-n-propenylalanine
  • Fmoc-(S)-2-(2-propenyl)alanine
  • Fmoc-(S)-2-(2-propenyl)Ala-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH
  • Fmoc-alpha-All-D-Ala-OH
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid
  • (S)-N-Fmoc-2-(2'-propenyl)alanine
  • (2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid
  • (S)-N-Fmoc-A-Allylalanine
  • 4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)-
  • N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine
  • Fmoc-α-Me-Gly(Allyl)-OH
  • (S)-N-Fmoc-2-(2'-propylenyl)alanine
  • 288617-71-0
  • α-Methyl Amino Acids