4-bromo-5-methyl-2-nitrophenol
- Product Name
- 4-bromo-5-methyl-2-nitrophenol
- CAS No.
- 182500-28-3
- Chemical Name
- 4-bromo-5-methyl-2-nitrophenol
- Synonyms
- 2-Nitro-5-methyl-4-bromophenol;4-bromo-5-methyl-2-nitrophenol;Phenol, 4-bromo-5-methyl-2-nitro-
- CBNumber
- CB02489881
- Molecular Formula
- C7H6BrNO3
- Formula Weight
- 232.03
- MOL File
- 182500-28-3.mol
4-bromo-5-methyl-2-nitrophenol Property
- Melting point:
- 126℃
- Boiling point:
- 293℃
- Density
- 1.755
- Flash point:
- 131℃
- storage temp.
- RT, stored under nitrogen
- pka
- 6.46±0.27(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2908990000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B405245
- Product name
- 4-Bromo-5-methyl-2-nitrophenol
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- FB154267
- Product name
- 4-Bromo-5-methyl-2-nitrophenol
- Packaging
- 1g
- Price
- $209
- Updated
- 2021/12/16
- Product number
- W3963
- Product name
- 4-Bromo-5-methyl-2-nitrophenol
- Packaging
- 1g
- Price
- $317
- Updated
- 2021/12/16
- Product number
- 119395
- Product name
- 4-Bromo-5-methyl-2-nitrophenol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- FB154267
- Product name
- 4-Bromo-5-methyl-2-nitrophenol
- Packaging
- 2g
- Price
- $363
- Updated
- 2021/12/16
4-bromo-5-methyl-2-nitrophenol Chemical Properties,Usage,Production
Synthesis
700-38-9
182500-28-3
The general procedure for the synthesis of 4-bromo-5-methyl-2-nitrophenol from 6-nitro-m-cresol was as follows: a solution of bromine (4.04 mL, 78 mmol) in acetic acid (10 mL) was slowly added dropwise to a stirred solution of 5-methyl-2-nitrophenol (6.0 g, 39.2 mmol) in acetic acid (60 mL) at 0 °C for a controlled time of 30 min. After the dropwise addition was completed, the reaction mixture was continued to be stirred at room temperature for 2 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting residue was dissolved in ethyl acetate (300 mL). Subsequently, the organic phase was washed sequentially with saturated sodium thiosulfate solution (2 x 50 mL), water (50 mL) and saturated brine (50 mL). The washed organic layer was dried with anhydrous sodium sulfate and filtered to remove the desiccant. The filtrate was concentrated by rotary evaporation to afford the title compound 4-bromo-5-methyl-2-nitrophenol in yellow solid form 9.0 g in 99% yield. The structure of the product was analyzed by 1HNMR (400 MHz, CDCl3) δ 10.46 (s, 1H), 8.29 (s, 1H), 7.08 (s, 1H), 2.46 (s, 3H) and GC-MS (m/z) 232,234 [M+. Br79,81] confirmed.
References
[1] Patent: US2016/145268, 2016, A1. Location in patent: Paragraph 0238
[2] Journal of the American Chemical Society, 1914, vol. 36, p. 1509
[3] Journal of the Chemical Society, 1914, vol. 105, p. 1891
[4] Journal of the American Chemical Society, 1922, vol. 44, p. 1794 Anm.7
4-bromo-5-methyl-2-nitrophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-bromo-5-methyl-2-nitrophenol manufacturers
- Product
- 4-bromo-5-methyl-2-nitrophenol 182500-28-3
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2025-04-16