6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
- Product Name
- 6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
- CAS No.
- 947248-68-2
- Chemical Name
- 6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
- Synonyms
- 2-AMino-6-broMo-[1,2,4]triazolo[1,5-a]pyridine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, 6-bromo-;6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine;6-BR0M0- [1,2, 4]TRIAZ0L0[l,5- A]PYRIDIN-2-AMINE;6-bromo- [1,2,4] triazole [1,5-A] pyridine-2-amine;6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine ISO 9001：2015 REACH
- CBNumber
- CB02500131
- Molecular Formula
- C6H5BrN4
- Formula Weight
- 213.03
- MOL File
- 947248-68-2.mol
6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Property
- Density
- 2.09
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- 4.00±0.30(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C6H5BrN4/c7-4-1-2-5-9-6(8)10-11(5)3-4/h1-3H,(H2,8,10)
- InChIKey
- XHBQNLHFUPSZNL-UHFFFAOYSA-N
- SMILES
- C12=NC(N)=NN1C=C(Br)C=C2
- CAS DataBase Reference
- 947248-68-2
Safety
- WGK Germany
- 3
- HS Code
- 2921511990
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SYX00250
- Product name
- 6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $185
- Updated
- 2025/07/31
- Product number
- B614665
- Product name
- 6-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B614665
- Product name
- 6-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 25g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- B614665
- Product name
- 6-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 2.5g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB42487
- Product name
- 6-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Chemical Properties,Usage,Production
Synthesis
1010120-60-1
947248-68-2
Step b) Synthesis of 6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Ethyl {[(5-bromopyridin-2-yl)amino]thiocarbonyl}carbamate (12.3 g, 40.4 mmol), hydroxylamine hydrochloride (14.1 g, 202 mmol), and N,N-diisopropylethylamine (DIEA, 15.7 g, 122 mmol) were suspended in a solvent mixture of methanol (MeOH) and ethanol (EtOH) (1:1, v/v). 200 mL). The reaction mixture was stirred at room temperature for 2 h, then warmed up to 70 °C and continued the reaction for 3 h. The reaction was carried out under reduced pressure by distillation. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in a solvent mixture of dioxane and water (1:1, v/v) and filtered to afford the target product 6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine as an off-white powder (42.6 g, 99% yield). The product was analyzed by high performance liquid chromatography (HPLC) with a retention time (Rt) of 1.1 min (purity 99.8%). Liquid chromatography-mass spectrometry (LC/MS) analysis showed that the molecular ion peak [M+H]+ (ESI) was 215.3.
References
[1] Patent: WO2010/100144, 2010, A1. Location in patent: Page/Page column 102-103
[2] Patent: WO2009/133127, 2009, A1. Location in patent: Page/Page column 85
[3] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 126-127
[4] Patent: WO2013/41472, 2013, A1. Location in patent: Page/Page column 36
[5] Patent: WO2009/68482, 2009, A1. Location in patent: Page/Page column 43-44
6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Preparation Products And Raw materials
Raw materials
Preparation Products
6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Suppliers
- Tel
- +86(21)5895 0110 19945755304
- sales@chemany.com
- Country
- China
- ProdList
- 9984
- Advantage
- 58
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 18986259541 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3744
- Advantage
- 58
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9519
- Advantage
- 58
- Tel
- 18652989687
- Fax
- +86-25-52131256
- sales@norris-pharm.com
- Country
- China
- ProdList
- 8878
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9341
- Advantage
- 55
- Tel
- 86(512)5235 8471 17715136450
- Fax
- 86(512)5235 6881
- sales@shiyabiopharm.com
- Country
- China
- ProdList
- 4169
- Advantage
- 58
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
View Lastest Price from 6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine manufacturers
- Product
- 6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine 947248-68-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 500kgs/month
- Release date
- 2021-11-14
- Product
- 6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine 947248-68-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- KG/T
- Release date
- 2019-12-18