Δ2-Cefepime
- Product Name
- Δ2-Cefepime
- CAS No.
- 88040-25-9
- Chemical Name
- Δ2-Cefepime
- Synonyms
- Δ2-Cefepime;Δ2-Cefepime;Δ2-CefepiMe Etherate;Cefepime Δ - 3 Isomer;Cefepime Δ - 3 Isomer;Δ2-CefepiMe Etherate Dihydrochloride Salt;1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]Methyl]-1-MethylpyrrolidiniuM Inner Salt Etherate;(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate,ethoxyethane
- CBNumber
- CB02508627
- Molecular Formula
- C23H34N6O6S2
- Formula Weight
- 554.68266
- MOL File
- 88040-25-9.mol
Δ2-Cefepime Property
- Melting point:
- >151°C (dec.)
- storage temp.
- Amber Vial, -20°C Freezer, Under Inert Atmosphere
- solubility
- Water (Slightly)
- form
- Solid
- color
- White to Off-White
- InChIKey
- DBCVQAGQPYVVDA-XVKMNWMGSA-N
N-Bromosuccinimide Price
- Product number
- C242743
- Product name
- Δ2-Cefepime
- Packaging
- 2.5mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 7513DU
- Product name
- (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate;ethoxyethane
- Packaging
- 1mg
- Price
- $211
- Updated
- 2021/12/16
- Product number
- FC19856
- Product name
- Delta2-Cefepime etherate
- Packaging
- 2mg
- Price
- $218.1
- Updated
- 2021/12/16
- Product number
- FC19856
- Product name
- Delta2-Cefepime etherate
- Packaging
- 5mg
- Price
- $396.4
- Updated
- 2021/12/16
- Product number
- FC19856
- Product name
- Delta2-Cefepime etherate
- Packaging
- 10mg
- Price
- $720.8
- Updated
- 2021/12/16
Δ2-Cefepime Chemical Properties,Usage,Production
Uses
Δ2-Cefepime is the Δ2-isomer of Cefepime (C242750), a new series of cephalosporins.
Uses
The Δ2-isomer of Cefepime (C242750), a new series of cephalosporins.
Preparation
First, cefepime and N-trimethylsilylacetamide were added to dichloromethane for 0.5 h. Subsequently, triethylamine dissolved in dichloromethane was added to the reaction system between 2-5 °C. Adjust the temperature to 2-5 °C and react for 24 h. After adding water, the aqueous layer was separated, and the aqueous phase was washed with methylene chloride. Wait for the solution to cool to 2-5 °C and adjust the pH=3 with sulfuric acid. Stir the resulting slurry for 2h. Filter to collect the solids and wash with water, adjust the pH=7.5-8.0 with sodium bicarbonate aqueous solution, add carbon, and stir for 30 min. Filter the mixture to collect the filtrate and adjust pH=3 with sulfuric acid. Finally, the solids are filtered and collected, and product Δ2-Cefepime is obtained by washing and drying.