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4-Hydroxy Xylazine

Product Name
4-Hydroxy Xylazine
CAS No.
145356-32-7
Chemical Name
4-Hydroxy Xylazine
Synonyms
4-Hydroxy Xylazine;Xylazine Impurity 10;4-[(5,6-Dihydro-4H-1,3-thiazin-2-yl)aMino]-3,5-diMethylphenol;Phenol, 4-[(5,6-dihydro-4H-1,3-thiazin-2-yl)amino]-3,5-dimethyl-;N-(4-hydroxy-2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
CBNumber
CB02510543
Molecular Formula
C12H16N2OS
Formula Weight
236.33
MOL File
145356-32-7.mol
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4-Hydroxy Xylazine Property

Melting point:
250-252°C (dec.)
Boiling point:
391.7±52.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.85±0.36(Predicted)
color 
Off-White to Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22920
Product name
4-hydroxy Xylazine
Purity
≥98%
Packaging
500μg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
22920
Product name
4-hydroxy Xylazine
Purity
≥98%
Packaging
1mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
22920
Product name
4-hydroxy Xylazine
Purity
≥98%
Packaging
5mg
Price
$755
Updated
2024/03/01
TRC
Product number
H996300
Product name
4-HydroxyXylazine
Packaging
10mg
Price
$1295
Updated
2021/12/16
TRC
Product number
H996300
Product name
4-HydroxyXylazine
Packaging
2mg
Price
$310
Updated
2021/12/16
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4-Hydroxy Xylazine Chemical Properties,Usage,Production

Description

4-hydroxy Xylazine is a metabolite of xylazine (Item Nos. 14113 | 22641). Xylazine is an agonist of α2-adrenergic receptors used for sedation, anesthesia, and analgesia in non-human mammals. 4-hydroxy Xylazine has been used as a marker for xylazine doping in MS analysis of equine urine.

Chemical Properties

Off-White to Tan Solid

Uses

A major metabolite of Xylazine (X748000).

References

[1] A E MUTLIB. Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.[J]. Drug Metabolism and Disposition, 1992, 20 6: 840-848.
[2] M.-H. SPYRIDAKI . Determination of xylazine and its metabolites by GC–MS in equine urine for doping analysis[J]. Journal of pharmaceutical and biomedical analysis, 2004, 35 1: Pages 107-116. DOI: 10.1016/j.jpba.2003.12.007
[3] W. H. KWOK. Screening of over 100 drugs in horse urine using automated on-line solid-phase extraction coupled to liquid chromatography-high resolution mass spectrometry for doping control.[J]. Journal of Chromatography A, 2017, 44 1: 89-101. DOI: 10.1016/j.chroma.2017.02.020
[4] RAIMO VIRTANEN . Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist[J]. European journal of pharmacology, 1988, 150 1: Pages 9-14. DOI: 10.1016/0014-2999(88)90744-3
[5] CLAIRE A RICHARDSON  Paul A F. Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: are we making progress?[J]. Atla-Alternatives To Laboratory Animals, 2005, 33 2: 119-127. DOI: 10.1177/026119290503300207
[6] DVM A V, DVSC. Alpha-2 Agonists as Pain Therapy in Horses[J]. Veterinary Clinics of North America-Equine Practice, 2010, 26 3: Pages 515-532. DOI: 10.1016/j.cveq.2010.07.003

4-Hydroxy Xylazine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy Xylazine Suppliers

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145356-32-7, 4-Hydroxy XylazineRelated Search:


  • 4-Hydroxy Xylazine
  • 4-[(5,6-Dihydro-4H-1,3-thiazin-2-yl)aMino]-3,5-diMethylphenol
  • Phenol, 4-[(5,6-dihydro-4H-1,3-thiazin-2-yl)amino]-3,5-dimethyl-
  • Xylazine Impurity 10
  • N-(4-hydroxy-2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
  • 145356-32-7
  • Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds