ChemicalBook > CAS DataBase List > 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

Product Name
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
CAS No.
164658-13-3
Chemical Name
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
Synonyms
CS-506;CGP 60474;CGP60474 ，E2642;CGP-60474;CGP 60474;CGP60474, 10 mM in DMSO;3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol;3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol;3-((4-(2-((3-Chlorophenyl)amino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol;1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-
CBNumber
CB02514596
Molecular Formula
C18H18ClN5O
Formula Weight
355.82
MOL File
164658-13-3.mol
More
Less

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Property

Melting point:
144-147℃
Boiling point:
630.6±65.0 °C(Predicted)
Density 
1.356
storage temp. 
2-8°C(protect from light)
solubility 
Soluble in DMSO
form 
Powder
pka
14.93±0.10(Predicted)
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Tocris
Product number
5471
Product name
CGP60474
Purity
≥98%(HPLC)
Packaging
10
Price
$169
Updated
2021/12/16
Tocris
Product number
5471
Product name
CGP60474
Purity
≥98%(HPLC)
Packaging
50
Price
$711
Updated
2021/12/16
TRC
Product number
C291780
Product name
CGP60474
Packaging
100mg
Price
$1000
Updated
2021/12/16
ChemScene
Product number
CS-0024
Product name
CGP60474
Purity
98.70%
Packaging
5mg
Price
$119
Updated
2021/12/16
ChemScene
Product number
CS-0024
Product name
CGP60474
Purity
98.70%
Packaging
10mg
Price
$168
Updated
2021/12/16
More
Less

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Chemical Properties,Usage,Production

Uses

CGP 60474 is type of protein kinase C inhibitor (ckd1/cdk2) used in the treatment of different cancers

Definition

ChEBI: 3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol is a substituted aniline.

in vivo

CGP-60474 (10mg/kg; i.p.) inhibits the IL-6 level and increases the survival rate in the LPS endotoxemia model[2].

Animal Model:C57Bl/6 mice (LPS endotoxemia model)[2]
Dosage:10mg/kg
Administration:I.p.
Result:Had a higher survival rate.

IC 50

CDK1-Cyclin B: 26 nM (IC50); CDK2/cyclinE: 3 nM (IC50); cdk2/cyclin A: 4 nM (IC50); CDK4/cyclin D: 216 nM (IC50); Cdk5/p25: 10 nM (IC50); CDK7/cyclin H: 200 nM (IC50); CDK9/cycT: 13 nM (IC50); PKC

storage

Store at -20°C

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol Suppliers

China 95 India 1 United Kingdom 1 United States 12 Global 109
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
26300
Advantage
65
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4810
Advantage
55
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
981
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
More
Less

View Lastest Price from 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol manufacturers

Career Henan Chemical Co
Product
3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol 164658-13-3
Price
US $1.00/g
Min. Order
1g
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-10
Career Henan Chemical Co
Product
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol 164658-13-3
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-10

164658-13-3, 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanolRelated Search:

CHLOROPHENYLSILANE 4,4'-DDT

  • 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
  • CGP 60474
  • CS-506
  • 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol
  • CGP-60474;CGP 60474
  • 1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-
  • 3-((4-(2-((3-Chlorophenyl)amino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol
  • CGP60474, 10 mM in DMSO
  • CGP60474 ，E2642
  • 164658-13-3