ChemicalBook > CAS DataBase List > Nitidanin
Nitidanin
- Product Name
- Nitidanin
- CAS No.
- 171674-89-8
- Chemical Name
- Nitidanin
- Synonyms
- Nitidanin;(2R,3R)-rel-2,3-Dihydro-3-(4-hydroxy-3,5-dimethoxyphenyl)-6-[(1E)-3-hydroxy-1-propen-1-yl]-8-methoxy-1,4-benzodioxin-2-methanol;1,4-Benzodioxin-2-methanol, 2,3-dihydro-3-(4-hydroxy-3,5-dimethoxyphenyl)-6-[(1E)-3-hydroxy-1-propen-1-yl]-8-methoxy-, (2R,3R)-rel-
- CBNumber
- CB02519900
- Molecular Formula
- C21H24O8
- Formula Weight
- 404.41
- MOL File
- 171674-89-8.mol
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Nitidanin Property
- Melting point:
- 240 °C
- Boiling point:
- 622.2±55.0 °C(Predicted)
- Density
- 1.304±0.06 g/cm3(Predicted)
- pka
- 9.70±0.40(Predicted)
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Nitidanin Chemical Properties,Usage,Production
Uses
Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC50 values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection[1][2].
IC 50
Plasmodium
References
[1] Ma C, et al. Antimalarial compounds from Grewia bilamellata. J Nat Prod. 2006 Mar;69(3):346-50. DOI:10.1021/np050313d
[2] Pilkington LI, et al. 1,4-Benzodioxane Lignans: An Efficient, Asymmetric Synthesis of Flavonolignans and Study of Neolignan Cytotoxicity and Antiviral Profiles. J Nat Prod. 2018 Dec 28;81(12):2630-2637. DOI:10.1021/acs.jnatprod.8b00416
Nitidanin Preparation Products And Raw materials
Raw materials
Preparation Products
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