ChemicalBook > CAS DataBase List > (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate

(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate

Product Name
(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
CAS No.
618061-76-0
Chemical Name
(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
Synonyms
101077;(S)-Diethyl (2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetr...;(S)-Diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamin;diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetra-hydrofuran-3-yl)oxy)quinazolin-6-yl)am;N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-diethoxyphosphorylacetamide;(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate;Diethyl {[4-(3-Chloro-4-Fluoro-PhenylaMino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-YlcarbaMoyl]-Methyl}-Phosphonate;diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate;P-[2-[[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]amino]-2-oxoethyl]phosphonic acid diethyl ester;Phosphonic acid, P-[2-[[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]aMino]-2-oxoethyl]-, diethyl ester
CBNumber
CB02522085
Molecular Formula
C24H27ClFN4O6P
Formula Weight
552.92
MOL File
618061-76-0.mol
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(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate Property

Density 
1.425
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
InChIKey
FNGRCLBEXKFSST-INIZCTEOSA-N
SMILES
P(CC(NC1C(O[C@H]2CCOC2)=CC2C(C=1)=C(NC1=CC=C(F)C(Cl)=C1)N=CN=2)=O)(=O)(OCC)OCC
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Ark Pharm
Product number
AK185750
Product name
(S)-Diethyl2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
Purity
95+%
Packaging
100mg
Price
$253
Updated
2021/12/16
Matrix Scientific
Product number
120697
Product name
(S)-Diethyl2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
Purity
97%
Packaging
50mg
Price
$396
Updated
2021/12/16
Matrix Scientific
Product number
120697
Product name
(S)-Diethyl2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
Purity
97%
Packaging
100mg
Price
$540
Updated
2021/12/16
Ark Pharm
Product number
AK185750
Product name
(S)-Diethyl2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
Purity
95+%
Packaging
1g
Price
$1007
Updated
2021/12/16
Arctom
Product number
AS030378
Product name
(S)-Diethyl2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
Purity
95%
Packaging
1g
Price
$1091
Updated
2021/12/16
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(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate Chemical Properties,Usage,Production

Uses

Diethyl (S)-2-Amino-2-oxoethyl Phosphonate Afatinib is an impurity of Afatinib (A355300), which is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate Suppliers

Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ:63313187
Email
63313187@qq.com
Country
China
ProdList
1986
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58
Arizest(Shanghai)Pharmatech Co.,Ltd
Tel
60753300-53010 13671599112
Email
geshi.zhuang@acebright.com
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China
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97
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58
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
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14103
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Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com (International market)
Country
China
ProdList
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ChemShuttle, Inc.
Tel
0510-83588313-802 18800520310;
Email
sales@chemshuttle.com
Country
China
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T&W GROUP
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021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
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China
ProdList
9895
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58
Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
Fax
+86 21 50676805
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China
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9891
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58
Shanghai Famo Bio-chemical Technology Company Ltd.
Tel
021-021-36680027 15800370750
Email
1706640024@qq.com
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China
ProdList
546
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CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
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China
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1785
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58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
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View Lastest Price from (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate manufacturers

Career Henan Chemical Co
Product
(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate 618061-76-0
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2018-07-31

618061-76-0, (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonateRelated Search:


  • Diethyl {[4-(3-Chloro-4-Fluoro-PhenylaMino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-YlcarbaMoyl]-Methyl}-Phosphonate
  • Phosphonic acid, P-[2-[[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]aMino]-2-oxoethyl]-, diethyl ester
  • P-[2-[[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]amino]-2-oxoethyl]phosphonic acid diethyl ester (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethy
  • diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate
  • (S)-Diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamin
  • P-[2-[[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]amino]-2-oxoethyl]phosphonic acid diethyl ester
  • N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-diethoxyphosphorylacetamide
  • (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
  • diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetra-hydrofuran-3-yl)oxy)quinazolin-6-yl)am
  • 101077
  • (S)-Diethyl (2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetr...
  • 618061-76-0
  • 618081-76-0
  • C24H27ClFN4O6P