(2-Hydroxyphenyl)acetonitrile
- Product Name
- (2-Hydroxyphenyl)acetonitrile
- CAS No.
- 14714-50-2
- Chemical Name
- (2-Hydroxyphenyl)acetonitrile
- Synonyms
- 2-Hydroxybenzyl nitrile;2-Hydroxybenzeneacetonitrile;(2-Hydroxyphenyl)acetonitrile;Benzeneacetonitrile, 2-hydroxy-;2-(2-hydroxyphenyl)acetonitrile
- CBNumber
- CB02549585
- Molecular Formula
- C8H7NO
- Formula Weight
- 133.15
- MOL File
- 14714-50-2.mol
(2-Hydroxyphenyl)acetonitrile Property
- Melting point:
- 122-123℃
- Boiling point:
- 285.2±15.0℃ (760 Torr)
- Density
- 1.167±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 126.3±20.4℃
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 9.46±0.30(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- H952983
- Product name
- (2-Hydroxyphenyl)acetonitrile
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- CHM0387595
- Product name
- 2-(2-HYDROXYPHENYL)ACETONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.19
- Updated
- 2021/12/16
- Product number
- CM132986
- Product name
- 2-(2-hydroxyphenyl)acetonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $589
- Updated
- 2021/12/16
- Product number
- 14714502
- Product name
- 2-(2-Hydroxyphenyl)acetonitrile
- Packaging
- 5g
- Price
- $655.2
- Updated
- 2021/12/16
- Product number
- CM132986
- Product name
- 2-(2-hydroxyphenyl)acetonitrile
- Purity
- 97%
- Packaging
- 1g
- Price
- $234
- Updated
- 2021/12/16
(2-Hydroxyphenyl)acetonitrile Chemical Properties,Usage,Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038
Synthesis
773837-37-9
90-01-7
14714-50-2
In a 2L round bottom flask reactor, salicyl alcohol (100 g, 806 mmol), sodium cyanide (43.4 g, 886 mmol) and dimethylformamide (1000 mL) were added and the mixture was stirred and reacted at 120°C for 4 hours. Upon completion of the reaction, extraction was carried out using water and ethyl acetate. The organic phase was concentrated and purified by column chromatography to afford 2-hydroxyphenylacetonitrile (90 g, 84% yield).
References
[1] Patent: CN107459523, 2017, A. Location in patent: Paragraph 0285; 0286; 0287; 0288; 0289
[2] Patent: KR2018/14985, 2018, A. Location in patent: Paragraph 0550-0556
[3] Patent: KR2016/26661, 2016, A. Location in patent: Paragraph 0455-0461
[4] Tetrahedron, 2015, vol. 71, # 26-27, p. 4432 - 4437
(2-Hydroxyphenyl)acetonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2-Hydroxyphenyl)acetonitrile manufacturers
- Product
- (2-Hydroxyphenyl)acetonitrile 14714-50-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.0%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26
- Product
- (2-Hydroxyphenyl)acetonitrile 14714-50-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-14