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(2-Hydroxyphenyl)acetonitrile

Product Name
(2-Hydroxyphenyl)acetonitrile
CAS No.
14714-50-2
Chemical Name
(2-Hydroxyphenyl)acetonitrile
Synonyms
2-Hydroxybenzyl nitrile;2-Hydroxybenzeneacetonitrile;(2-Hydroxyphenyl)acetonitrile;Benzeneacetonitrile, 2-hydroxy-;2-(2-hydroxyphenyl)acetonitrile
CBNumber
CB02549585
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
14714-50-2.mol
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(2-Hydroxyphenyl)acetonitrile Property

Melting point:
122-123℃
Boiling point:
285.2±15.0℃ (760 Torr)
Density 
1.167±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
126.3±20.4℃
storage temp. 
Inert atmosphere,Room Temperature
pka
9.46±0.30(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
H952983
Product name
(2-Hydroxyphenyl)acetonitrile
Packaging
50mg
Price
$55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0387595
Product name
2-(2-HYDROXYPHENYL)ACETONITRILE
Purity
95.00%
Packaging
5MG
Price
$500.19
Updated
2021/12/16
Chemenu
Product number
CM132986
Product name
2-(2-hydroxyphenyl)acetonitrile
Purity
97%
Packaging
5g
Price
$589
Updated
2021/12/16
Alichem
Product number
14714502
Product name
2-(2-Hydroxyphenyl)acetonitrile
Packaging
5g
Price
$655.2
Updated
2021/12/16
Chemenu
Product number
CM132986
Product name
2-(2-hydroxyphenyl)acetonitrile
Purity
97%
Packaging
1g
Price
$234
Updated
2021/12/16
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(2-Hydroxyphenyl)acetonitrile Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038

Synthesis

773837-37-9

90-01-7

14714-50-2

In a 2L round bottom flask reactor, salicyl alcohol (100 g, 806 mmol), sodium cyanide (43.4 g, 886 mmol) and dimethylformamide (1000 mL) were added and the mixture was stirred and reacted at 120°C for 4 hours. Upon completion of the reaction, extraction was carried out using water and ethyl acetate. The organic phase was concentrated and purified by column chromatography to afford 2-hydroxyphenylacetonitrile (90 g, 84% yield).

References

[1] Patent: CN107459523, 2017, A. Location in patent: Paragraph 0285; 0286; 0287; 0288; 0289
[2] Patent: KR2018/14985, 2018, A. Location in patent: Paragraph 0550-0556
[3] Patent: KR2016/26661, 2016, A. Location in patent: Paragraph 0455-0461
[4] Tetrahedron, 2015, vol. 71, # 26-27, p. 4432 - 4437

(2-Hydroxyphenyl)acetonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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(2-Hydroxyphenyl)acetonitrile Suppliers

Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
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0513-82104991 18912868361
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QQ1907456386
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sales11@btcpharm.com
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China
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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18270980682
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021 51613951
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mlcheng@sunwaypharm.cn
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China
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8669
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Shanghai civi chemical technology co.,Ltd
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86-21-34053660
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sale@labgogo.com
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
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(1)02557626880
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cfzhang@aikonchem.com
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Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
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7865
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
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ChemStrong Scientific Co.,Ltd
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Sichuan Wei Keqi Biological Technology Co., Ltd.
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028-81700200 18116577057
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ShangHai AmK Pharmaceutical Technology Co., Ltd.
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Jinan LuoHe PharmaTech Co., Ltd.
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View Lastest Price from (2-Hydroxyphenyl)acetonitrile manufacturers

Honest Joy Holdings Limited
Product
(2-Hydroxyphenyl)acetonitrile 14714-50-2
Price
US $0.00/KG
Min. Order
1KG
Purity
97.0%
Supply Ability
100 tons
Release date
2022-01-26
Career Henan Chemical Co
Product
(2-Hydroxyphenyl)acetonitrile 14714-50-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-14

14714-50-2, (2-Hydroxyphenyl)acetonitrileRelated Search:


  • (2-Hydroxyphenyl)acetonitrile
  • 2-(2-hydroxyphenyl)acetonitrile
  • Benzeneacetonitrile, 2-hydroxy-
  • 2-Hydroxybenzyl nitrile
  • 2-Hydroxybenzeneacetonitrile
  • 14714-50-2