4-Bromo-5-fluoro-2-nitrophenol
- Product Name
- 4-Bromo-5-fluoro-2-nitrophenol
- CAS No.
- 1016234-87-9
- Chemical Name
- 4-Bromo-5-fluoro-2-nitrophenol
- Synonyms
- 4-Bromo-2-nitro-5-fluorophenol;4-Bromo-5-fluoro-2-nitrophenol;2-nitro-4-bromo-5-fluorophenol;Phenol, 4-bromo-5-fluoro-2-nitro-;4-Bromo-5-fluoro-2-nitrophenol 97%;5-Bromo-4-fluoro-2-hydroxynitrobenzene
- CBNumber
- CB02564773
- Molecular Formula
- C6H3BrFNO3
- Formula Weight
- 236
- MOL File
- 1016234-87-9.mol
4-Bromo-5-fluoro-2-nitrophenol Property
- Boiling point:
- 266.8±35.0 °C(Predicted)
- Density
- 1.965±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 5.35±0.27(Predicted)
- form
- crystalline solid
- color
- Bright lemon to faint lime
Safety
- HS Code
- 2908990000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B688823
- Product name
- 4-Bromo-5-fluoro-2-nitrophenol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC51153
- Product name
- 4-Bromo-5-fluoro-2-nitrophenol
- Purity
- 97%
- Packaging
- 1g
- Price
- $67
- Updated
- 2021/12/16
- Product number
- 4654-B-Y2
- Product name
- 4-Bromo-5-fluoro-2-nitrophenol
- Packaging
- 1g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- 088178
- Product name
- 4-Bromo-5-fluoro-2-nitrophenol
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- Z6367
- Product name
- 4-Bromo-5-fluoro-2-nitrophenol
- Packaging
- 1g
- Price
- $157
- Updated
- 2021/12/16
4-Bromo-5-fluoro-2-nitrophenol Chemical Properties,Usage,Production
Synthesis
121219-03-2
1016234-87-9
General procedure for the synthesis of 4-bromo-5-fluoro-2-nitrophenol from 4-bromo-3-fluorophenol: To a stirred mixture of 4-bromo-3-fluorophenol (10.23 g, 53.56 mmol), dichloromethane (108 mL), and sulfuric acid (6 mL, 107 mmol) was added slowly 65% nitric acid (3.8 mL, 53.6 mmol) at 0 °C. The reaction mixture was kept stirred at 0°C for 1 hour. After completion of the reaction, the mixture was diluted with water. The aqueous phase was extracted three times with dichloromethane and the organic layers were combined. The organic layer was concentrated and the resulting residue was purified by medium pressure liquid chromatography (MPLC) using a 10:1 to 2:1 gradient elution of hexane:ethyl acetate to afford 4-bromo-5-fluoro-2-nitrophenol (9.47 g, 75% yield) as a yellow solid.
References
[1] Patent: WO2015/171610, 2015, A2. Location in patent: Paragraph 000434
[2] Patent: WO2008/37746, 2008, A1. Location in patent: Page/Page column 15
[3] Patent: US2008/90804, 2008, A1. Location in patent: Page/Page column 6-7
[4] Patent: WO2008/37746, 2008, A1. Location in patent: Page/Page column 15
[5] Patent: WO2010/130773, 2010, A2. Location in patent: Page/Page column 65-66
4-Bromo-5-fluoro-2-nitrophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Bromo-5-fluoro-2-nitrophenol manufacturers
- Product
- 4-Bromo-5-fluoro-2-nitrophenol 1016234-87-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
- Product
- 4-Bromo-5-fluoro-2-nitrophenol 1016234-87-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27