5,8-DibroMoiMidazo[1,2-a]pyrazine
- Product Name
- 5,8-DibroMoiMidazo[1,2-a]pyrazine
- CAS No.
- 957344-74-0
- Chemical Name
- 5,8-DibroMoiMidazo[1,2-a]pyrazine
- Synonyms
- 5,8-DibroMoiMidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 5,8-dibromo-;5-bromoimidazo[1,2-a]pyrazin-8-amine
- CBNumber
- CB02595522
- Molecular Formula
- C6H3Br2N3
- Formula Weight
- 276.92
- MOL File
- 957344-74-0.mol
5,8-DibroMoiMidazo[1,2-a]pyrazine Property
- Density
- 2.35±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.30±0.30(Predicted)
- Appearance
- Light brown to light yellow Solid
Safety
- HS Code
- 2933998090
N-Bromosuccinimide Price
- Product number
- OR926842
- Product name
- 5,8-Dibromoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 3H32-9-DX
- Product name
- 5,8-Dibromoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- OR926842
- Product name
- 5,8-Dibromoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 3H32-9-DX
- Product name
- 5,8-Dibromoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $128
- Updated
- 2021/12/16
- Product number
- 6535AC
- Product name
- 5,8-Dibromoimidazo[1,2-a]pyrazine
- Packaging
- 100mg
- Price
- $143
- Updated
- 2021/12/16
5,8-DibroMoiMidazo[1,2-a]pyrazine Chemical Properties,Usage,Production
Synthesis
957230-70-5
2032-35-1
957344-74-0
General procedure for the synthesis of 5,8-dibromoimidazo[1,2-a]pyrazines from 2,5-dibromo-3-aminopyrazines and bromoacetaldehyde diethyl acetal: 3,6-dibromopyrazin-2-ylamine (4.0 g, 15.80 mmol) and bromoacetaldehyde diethyl acetal (3.7 mL, 24.00 mmol) were dissolved in a mixture of tetrahydrofuran (5.3 mL) and distilled water (53 mL ) in a solvent mixture. The reaction mixture was stirred at 120 °C for 4 hours. Upon completion of the reaction, the reaction solution was neutralized by addition of saturated aqueous sodium bicarbonate. The resulting solid was collected by filtration, washed with distilled water and dried to give 5,8-dibromoimidazo[1,2-a]pyrazine (2.75 g).
References
[1] Patent: US2009/286798, 2009, A1. Location in patent: Page/Page column 27
[2] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 6, p. 2266 - 2270
[3] Patent: KR2015/113801, 2015, A. Location in patent: Paragraph 0127-0130
5,8-DibroMoiMidazo[1,2-a]pyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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