ChemicalBook > CAS DataBase List > Ethyl 5-phenyloxazole-2-carboxylate

Ethyl 5-phenyloxazole-2-carboxylate

Product Name: Ethyl 5-phenyloxazole-2-carboxylate
CAS No.: 13575-16-1
Chemical Name: Ethyl 5-phenyloxazole-2-carboxylate
Synonyms: Ethyl 5-phenyloxazole-2-carboxylate;methyl 5-phenyloxazole-2-carboxylate;Ethyl 5-phenyl-1,3-oxazole-2-carboxylate;2-Oxazolecarboxylic acid, 5-phenyl-, ethyl ester
CBNumber: CB02595597
Molecular Formula: C12H11NO3
Formula Weight: 217.22
MOL File: 13575-16-1.mol

Less

Ethyl 5-phenyloxazole-2-carboxylate Property

Melting point:: 60 - 62°C
Boiling point:: 344.8±35.0 °C(Predicted)
Density: 1.173±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: -1.84±0.10(Predicted)
Appearance: White to off-white Solid

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: E938795
Product name: Ethyl5-phenyloxazole-2-carboxylate
Packaging: 250mg
Price: $330
Updated: 2021/12/16

AK Scientific

Product number: 6156CU
Product name: Ethyl5-phenyloxazole-2-carboxylate
Packaging: 250mg
Price: $312
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0118608
Product name: ETHYL 5-PHENYLOXAZOLE-2-CARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $497.63
Updated: 2021/12/16

Matrix Scientific

Product number: 136542
Product name: Ethyl 5-phenyl-1,3-oxazole-2-carboxylate
Purity: 95%
Packaging: 1g
Price: $524
Updated: 2021/12/16

Matrix Scientific

Product number: 136542
Product name: Ethyl 5-phenyl-1,3-oxazole-2-carboxylate
Purity: 95%
Packaging: 2.500g
Price: $1144
Updated: 2021/12/16

Less

Ethyl 5-phenyloxazole-2-carboxylate Chemical Properties,Usage,Production

Synthesis

84978-66-5

13575-16-1

General procedure for the synthesis of ethyl 5-phenyl oxazole-2-carboxylate from ethyl [2-phenyl-2-oxoethyl]amino-2-oxoacetate: ethyl [2-phenyl-2-oxoethyl]amino-2-oxoacetate (16.5 g, 71 mmol) was dissolved in 200 mL of anhydrous toluene in a 1 L Parr reactor. To this solution 21 mL (225 mmol, 3.15 equiv) of phosphorus oxychloride (POCl3) was slowly added. The Parr reactor was sealed and the reaction mixture was heated in an oil bath at 110°C for 48 hours. Upon completion of the reaction, the solvent and the remaining phosphorous trichloride were removed by distillation under reduced pressure to give a brown oil. To this oily substance was added 300 mL of water, followed by extraction of the aqueous phase twice with 150 mL of dichloromethane. The organic phases were combined, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The resulting brown solid was recrystallized by 50 mL of ethanol to give a final 12.5 g of orange solid product in 80% yield. The product was identified by 1H NMR (300 MHz, DMSO-d6): δ 8.10 (s, 1H), 7.82 (d, J = 7.5 Hz, 2H), 7.55 (m, 3H), 4.43 (q, J = 7.1 Hz, 2H), 1.35 (t, J = 7.1 Hz, 3H). The mass spectrum (APCI+) showed m/z 218 ([M+H]+).

References

[1] Patent: WO2004/18428, 2004, A1. Location in patent: Page 362
[2] Patent: WO2005/61510, 2005, A1. Location in patent: Page/Page column 17
[3] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 334 - 347
[4] Yakugaku Zasshi, 1956, vol. 76, p. 307
[5] Chem.Abstr., 1956, p. 13874

Ethyl 5-phenyloxazole-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Ethyl 5-phenyloxazole-2-carboxylate Suppliers

China 38 India 1 United States 4 Global 43

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

ShangHai Wisacheam Pharmaceutical Co., Ltd.

Tel: 13817485796
Fax: QQ:895624079
Email: tim@wisacheampharm.com
Country: China
ProdList: 3592
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9856
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Shanghai Tengyi Chemical Technology Co., Ltd.

Tel: 17602173738
Fax: QQ:613666989
Email: 613666989@qq.com
Country: China
ProdList: 301
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Block Chemical Technology (Shanghai) Co., LTD

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 9673
Advantage: 58

Tianjin Nuokang Pharmaceutical Technology Co., Ltd.

Tel: 022-23989838 13810451150
Email: 44766350@qq.com
Country: China
ProdList: 2349
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Zhengzhou Alpha Chemical Co. LTD

Tel: 0371-0371-53732842 13383863444
Fax: QQ：3002612166
Email: 3002612166@qq.com
Country: China
ProdList: 9996
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Email: 2261760024@qq.com
Country: China
ProdList: 4900
Advantage: 58

Henan Dowon Chemical Technology Co., Ltd.

Tel: 16696119288
Email: 779113375@qq.com
Country: China
ProdList: 7236
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Huasige Pharmaceutical Technology Co., LTD

Tel: 13611612777
Email: 3627377363@qq.com
Country: China
ProdList: 4015
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Huzhou Chengbo Biotechnology Co., Ltd

Tel: 13626726938
Country: China
ProdList: 3879
Advantage: 58

Yantai Shengkailun Chemical Technology Co., Ltd.

Tel: 13356901049
Email: mark@sklnchem.cn
Country: China
ProdList: 9995
Advantage: 58

Huzhou Qingliu Silicate Biotechnology Co., Ltd

Tel: 13626726938
Email: 15952452933@163.cn
Country: China
ProdList: 4109
Advantage: 58

Hefei Qiming Pharmaceutical Technology Co., Ltd

Tel: 19810657371
Email: 123642210@qq.com
Country: China
ProdList: 818
Advantage: 58

Shanghai Likang New Materials Co., Limited

Tel: +86-16631818819 +86-17736933208
Email: 3684455296@qq.com
Country: China
ProdList: 9300
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Rhenbo (Shanghai) Biochemical Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6333
Advantage: 58

Beijing Luyuan Bird Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 15810802415@139.com
Country: CHINA
ProdList: 6750
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shxiyuanbio@163.com
Country: CHINA
ProdList: 6906
Advantage: 58

Shanghai Caiyou Industrial Co., Ltd.

Tel: --
Fax: --
Email: 15821073967@163.com
Country: CHINA
ProdList: 6748
Advantage: 58

Shanghai Jingke Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jingkehuaxue@163.com
Country: CHINA
ProdList: 6141
Advantage: 58

13575-16-1, Ethyl 5-phenyloxazole-2-carboxylateRelated Search:

Linezolid Mifepristone methyl 5-phenyl-1,3,4-oxadiazole-2-carboxylate 5-Benzyl-2-Boc-hexahydro-pyrrolo[3,4-C]pyrrole 5-PHENYLNICOTINIC ACID 5-PHENYL-1H-PYRROLE-2-CARBOXYLIC ACID 5-Phenyl-1,3,4-oxadiazole-2-carboxylic acid 5-PHENYL-2-FUROIC ACID 1-Benzothien-5-ylboronic acid metamifop

Ethyl 5-phenyloxazole-2-carboxylate

methyl 5-phenyloxazole-2-carboxylate

Ethyl 5-phenyl-1,3-oxazole-2-carboxylate

2-Oxazolecarboxylic acid, 5-phenyl-, ethyl ester

13575-16-1