CaproMorelin Tartrate
- Product Name
- CaproMorelin Tartrate
- CAS No.
- 193273-69-7
- Chemical Name
- CaproMorelin Tartrate
- Synonyms
- CS-2136;CP 424391-18;CP-424391 tartrate;CaproMorelin Tartrate;Capromorelin L-Tartrate;CP 424391-18; CP-424391 TARTRATE;Capromorelin tartrate (CP-424,391);Capromorelin Tartrate, 10 mM in DMSO;Inhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Capromorelin Tartrate;N-{2-[(3aS)-3a-benzyl-2-methyl-3-methylidene-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-1-(benzyloxy)-2-oxoethyl}-2-methylalaninamide 2,3-dihydroxybutanedioate (1:1)
- CBNumber
- CB02611352
- Molecular Formula
- C32H41N5O10
- Formula Weight
- 655.71
- MOL File
- 193273-69-7.mol
CaproMorelin Tartrate Property
- Melting point:
- >150oC (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Light Yellow
- Water Solubility
- H2O: 20mg/mL, clear
- Stability:
- Hygroscopic
- InChIKey
- MJGRJCMGMFLOET-GTNBBHPYNA-N
- SMILES
- [C@H](O)(C(=O)O)[C@@H](O)C(=O)O.C(C1C=CC=CC=1)[C@]12C(N(C)N=C1CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC1C=CC=CC=1)C2)=O |&1:0,5,17,28,r|
N-Bromosuccinimide Price
- Product number
- PZ0317
- Product name
- Capromorelin tartrate
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $111
- Updated
- 2025/07/31
- Product number
- PZ0317
- Product name
- Capromorelin tartrate
- Purity
- ≥98% (HPLC)
- Packaging
- 25 mg
- Price
- $447
- Updated
- 2025/07/31
- Product number
- C175645
- Product name
- CapromorelinTartrate
- Packaging
- 25mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- C175645
- Product name
- CapromorelinTartrate
- Packaging
- 1mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- C175645
- Product name
- CapromorelinTartrate
- Packaging
- 100mg
- Price
- $780
- Updated
- 2021/12/16
CaproMorelin Tartrate Chemical Properties,Usage,Production
Uses
Treatment and prevention of frailty; treatment of congestive heart failure; treatment of catabolic illness (growth hormone secretagogue).
Uses
Capromorelin Tartrate acts as a reagent used in the preparation of pyrazolopyridine amide growth hormone secretagogues for treatment of fibromyalgia
Biological Activity
Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM). In r at pituitary cells, Capromorlelin incudes growth hormone (GH) secretion with an EC50 of 3 nM. Capromorelin also increases gastric motility and has been studied recently in patients with spinal cord injuries.
in vivo
Dogs receiving capromorelin (30 mg/mL) have food consumption that is significantly greater than dogs treated with placebo. All dogs in the capromorelin group gain weight by 0.52 kg, more than that of placebo group[1]. Capromorelin shows enhanced intestinal absorption in rodent models and exhibits superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%][2]. Capromorelin stimulates GH release in anesthesized rat model, with ED50 of 0.05 mg/kg iv[2].
CaproMorelin Tartrate Preparation Products And Raw materials
Raw materials
Preparation Products
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