ChemicalBook > CAS DataBase List > CaproMorelin Tartrate

CaproMorelin Tartrate

Product Name
CaproMorelin Tartrate
CAS No.
193273-69-7
Chemical Name
CaproMorelin Tartrate
Synonyms
CS-2136;CP 424391-18;CP-424391 tartrate;CaproMorelin Tartrate;Capromorelin L-Tartrate;CP 424391-18; CP-424391 TARTRATE;Capromorelin tartrate (CP-424,391);Capromorelin Tartrate, 10 mM in DMSO;Inhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Capromorelin Tartrate;N-{2-[(3aS)-3a-benzyl-2-methyl-3-methylidene-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-1-(benzyloxy)-2-oxoethyl}-2-methylalaninamide 2,3-dihydroxybutanedioate (1:1)
CBNumber
CB02611352
Molecular Formula
C32H41N5O10
Formula Weight
655.71
MOL File
193273-69-7.mol
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CaproMorelin Tartrate Property

Melting point:
>150oC (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Light Yellow
Water Solubility 
H2O: 20mg/mL, clear
Stability:
Hygroscopic
InChIKey
MJGRJCMGMFLOET-GTNBBHPYNA-N
SMILES
[C@H](O)(C(=O)O)[C@@H](O)C(=O)O.C(C1C=CC=CC=1)[C@]12C(N(C)N=C1CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC1C=CC=CC=1)C2)=O |&1:0,5,17,28,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0317
Product name
Capromorelin tartrate
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$111
Updated
2025/07/31
Sigma-Aldrich
Product number
PZ0317
Product name
Capromorelin tartrate
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$447
Updated
2025/07/31
TRC
Product number
C175645
Product name
CapromorelinTartrate
Packaging
25mg
Price
$265
Updated
2021/12/16
TRC
Product number
C175645
Product name
CapromorelinTartrate
Packaging
1mg
Price
$50
Updated
2021/12/16
TRC
Product number
C175645
Product name
CapromorelinTartrate
Packaging
100mg
Price
$780
Updated
2021/12/16
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CaproMorelin Tartrate Chemical Properties,Usage,Production

Uses

Treatment and prevention of frailty; treatment of congestive heart failure; treatment of catabolic illness (growth hormone secretagogue).

Uses

Capromorelin Tartrate acts as a reagent used in the preparation of pyrazolopyridine amide growth hormone secretagogues for treatment of fibromyalgia

Biological Activity

Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM). In r at pituitary cells, Capromorlelin incudes growth hormone (GH) secretion with an EC50 of 3 nM. Capromorelin also increases gastric motility and has been studied recently in patients with spinal cord injuries.

in vivo

Dogs receiving capromorelin (30 mg/mL) have food consumption that is significantly greater than dogs treated with placebo. All dogs in the capromorelin group gain weight by 0.52 kg, more than that of placebo group[1]. Capromorelin shows enhanced intestinal absorption in rodent models and exhibits superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%][2]. Capromorelin stimulates GH release in anesthesized rat model, with ED50 of 0.05 mg/kg iv[2].

CaproMorelin Tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

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193273-69-7, CaproMorelin TartrateRelated Search:


  • CaproMorelin Tartrate
  • CP 424391-18
  • CP 424391-18; CP-424391 TARTRATE
  • CP-424391 tartrate
  • CS-2136
  • N-{2-[(3aS)-3a-benzyl-2-methyl-3-methylidene-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-1-(benzyloxy)-2-oxoethyl}-2-methylalaninamide 2,3-dihydroxybutanedioate (1:1)
  • Capromorelin tartrate (CP-424,391)
  • Inhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Capromorelin Tartrate
  • 2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-3a,4,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-5(3H)-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate
  • Capromorelin Tartrate, 10 mM in DMSO
  • Capromorelin L-Tartrate
  • 193273-69-7
  • C28H35N5O4C4H6O6
  • API