(R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid
- Product Name
- (R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid
- CAS No.
- 755039-56-6
- Chemical Name
- (R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid
- Synonyms
- dTAG Targeting Ligand 1;(R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid;Benzoic acid, 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-
- CBNumber
- CB02623591
- Molecular Formula
- C22H27N5O4
- Formula Weight
- 425.48
- MOL File
- 755039-56-6.mol
(R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid Property
- Boiling point:
- 710.7±70.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- form
- Solid
- pka
- 3+-.0.10(Predicted)
- InChIKey
- AMLPCXFISSPPBJ-MRXNPFEDSA-N
- SMILES
- C(O)(=O)C1=CC=C(NC2=NC=C3C(=N2)N(C2CCCC2)[C@H](CC)C(=O)N3C)C(OC)=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-M0330
- Product name
- (R)-4-(8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)-3-methoxybenzoicacid
- Packaging
- 1g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- CC00-6005
- Product name
- (R)-4-(8-Cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydro-pteridin-2-ylamino)-3-methoxy-benzoicacid
- Purity
- 97%
- Packaging
- 2.5g
- Price
- $2500
- Updated
- 2021/12/16
- Product number
- CM337849
- Product name
- 4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxybenzoicacid
- Purity
- 95%+
- Packaging
- 1g
- Price
- $2574
- Updated
- 2021/12/16
- Product number
- CM337849
- Product name
- 4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxybenzoicacid
- Purity
- 95%+
- Packaging
- 100mg
- Price
- $618
- Updated
- 2021/12/16
- Product number
- CM337849
- Product name
- 4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxybenzoicacid
- Purity
- 95%+
- Packaging
- 250mg
- Price
- $1287
- Updated
- 2021/12/16
(R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid Chemical Properties,Usage,Production
Uses
dTAG Targeting Ligand 1 (SUBSTITUTE SHEET 245) is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). dTAG Targeting Ligand 1 can be used for synthesis PROTACs[1].
References
[1] J. Bradner, et al. Targeting proteins are degraded to weaken the relevant bad inflammatory reaction of adoptive T cell therapy. CN108350062A.
(R)-4-(8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylaMino)-3-Methoxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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