ChemicalBook > CAS DataBase List > AZD2624
AZD2624
- Product Name
- AZD2624
- CAS No.
- 941690-55-7
- Chemical Name
- AZD2624
- Synonyms
- AZD2624;AZD4901;MLE-4901;Pavinetant;Pavinetant (MLE-4901);Pavinetant/MLE-4901/AZD2624/AZD4901;3-(methanesulfonamido)-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide;3-[(Methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide;4-Quinolinecarboxamide, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-
- CBNumber
- CB02627357
- Molecular Formula
- C26H25N3O3S
- Formula Weight
- 459.56
- MOL File
- 941690-55-7.mol
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AZD2624 Property
- Density
- 1.285±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:3): 0.25mg/mL; DMSO: 20mg/mL
- form
- A crystalline solid
- pka
- 1.35±0.30(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 23587
- Product name
- MLE-4901
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23587
- Product name
- MLE-4901
- Packaging
- 5mg
- Price
- $268
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23587
- Product name
- MLE-4901
- Packaging
- 10mg
- Price
- $401
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23587
- Product name
- MLE-4901
- Packaging
- 50mg
- Price
- $669
- Updated
- 2024/03/01
TRC
- Product number
- M368765
- Product name
- MLE-4901
- Packaging
- 250mg
- Price
- $1260
- Updated
- 2021/12/16
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AZD2624 Chemical Properties,Usage,Production
Uses
MLE-4901, is a neurokinin-3 receptor (NK3R) antagonist.
Definition
ChEBI: Pavinetant is a member of the class of quinolines that is the amide obtained by formal condensation of the carboxy group of 3-[(methanesulfonyl)amino]-2-phenylquinoline-4-carboxylic acid with the amino group of (1S)-1-phenylpropan-1-amine. A neurokinin-3 receptor antagonist that has been trialled as a potential drug for treatment of schizophrenia and menopausal symptoms. It has a role as a neurokinin-3 receptor antagonist and an antipsychotic agent. It is a member of quinolines, a secondary carboxamide, a sulfonamide and an aromatic amide.
IC 50
NK3
AZD2624 Preparation Products And Raw materials
Raw materials
Preparation Products
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