ChemicalBook > CAS DataBase List > CMX 001

CMX 001

Product Name
CMX 001
CAS No.
444805-28-1
Chemical Name
CMX 001
Synonyms
Brincidofovir (CMX001);CMX 001;HDP-CDV;CS-2275;HDP-HPMPC;HDP-cidofovir;Brincidofovir;CMX001(Brincidofovir);Fampridine Impurity 23;Hexadecyloxypropyl-cidofovir
CBNumber
CB02627690
Molecular Formula
C27H52N3O7P
Formula Weight
561.69
MOL File
444805-28-1.mol
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CMX 001 Property

Melting point:
> 177° C (dec.)
Boiling point:
688.6±65.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli
form 
Solid
pka
2.40±0.10(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3155
Product name
Brincidofovir
Purity
≥98% (HPLC)
Packaging
5MG
Price
$79
Updated
2023/06/20
Sigma-Aldrich
Product number
SML3155
Product name
Brincidofovir
Purity
≥98% (HPLC)
Packaging
25MG
Price
$319
Updated
2023/06/20
TRC
Product number
B677550
Product name
Brincidofovir
Packaging
10mg
Price
$945
Updated
2021/12/16
TRC
Product number
B677550
Product name
Brincidofovir
Packaging
25mg
Price
$2100
Updated
2021/12/16
ApexBio Technology
Product number
B1089
Product name
CMX001
Packaging
25mg
Price
$1800
Updated
2021/12/16
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CMX 001 Chemical Properties,Usage,Production

Uses

Brincidofovir is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells. Cytostatic, cytotoxic agent.

Biological Activity

cmx001 is a broad spectrum antiviral agent [1].cmx001 has been reported to be active in vitro against a broad range of viruses from all five families of dsdna viruses infecting human with ec50 values of 0.02μm, 0.0004μm, 17μm , 0.045μm and 0.07μm for adenovirus, herpesvirus, papillomavirus, polyomavirus and orthopoxvirus, respectively. in addition, cmx001 has been revealed to arrest disease progression by inhibiting viral dna replication and thereby reducing viral burden. apart from these, initial studies has been demonstrated the efficacy of cmx001 for pre-exposure and post-exposure prophylaxis in mouse, rabbit, cynomolgus monkeys and human [1].

References

[1]lanier r1, trost l, tippin t, lampert b, robertson a, foster s, rose m, painter w, o'mahony r, almond m, painter g.development of cmx001 for the treatment of poxvirus infections. viruses. 2010 dec; 2(12):2740-2762.

CMX 001 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CMX 001 manufacturers

shandong perfect biotechnology co.ltd
Product
Brincidofovir 444805-28-1
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
1kg
Release date
2023-08-02
R&D Scientific Inc.
Product
Brincidofovir 444805-28-1
Price
US $2500.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-11-12

444805-28-1, CMX 001Related Search:


  • Brincidofovir (CMX001)
  • Brincidofovir
  • CMX001(Brincidofovir)
  • CMX 001
  • HDP-cidofovir
  • Hexadecyloxypropyl-cidofovir
  • CMX 001 1-(hydroxymethyl)ethoxy]methyl]phosphonic acid mono[3-(hexadecyloxy)propyl] ester
  • (S)-[2-(4-amino-2-oxo-1,2-dihydro-1-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methylphosphonic acid 3-(hexadecyloxy)propyl monoester
  • [[(S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid mono[3-(hexadecyloxy)propyl] ester
  • CMX001;CMX 001;CMX-001;HDP-CIDOFOVIR;HEXADECYLOXYPROPYL-CIDOFOVIR
  • [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-(3-hexadecoxypropoxy)phosphinic acid
  • HDP-CDV
  • HDP-CDV; HDP-HPMPC;CMX001; BRINCIDOFOVIR; HDP-CIDOFOVIR;CMX 001
  • HDP-HPMPC
  • Brincidofovir, CMX-001, HDP-CDV
  • CS-2275
  • Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, mono[3-(hexadecyloxy)propyl] ester
  • Brincidofovir (CMX001, HDP CDV, HDPCDV)
  • CMX 001,DNA,lipid-conjugated,Brincidofovir,CMX-001,HSV,Herpes simplex virus,Cytomegalovirus,prodrug,Inhibitor,Orthopoxvirus,viruses,antiviral,CMV,inhibit,infection
  • 3-(Hexadecyloxy)propyl hydrogen ((((S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonate
  • ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)[3-(hexadecyloxy)propoxy]phosphinic acid
  • Fampridine Impurity 23
  • 444805-28-1
  • C27H52N3O7P