GSK962040
- Product Name
- GSK962040
- CAS No.
- 923565-21-3
- Chemical Name
- GSK962040
- Synonyms
- Camicil;Camicinal;GSK962040;Lopixibat chloride;GSK962040 (Camicinal;1-[4-[(3-Fluorophenyl)amino]-1-piperidinyl]-2-[4-[[(3S)-3-methyl-1-piperazinyl]methyl]phenyl]ethanone;Ethanone, 1-[4-[(3-fluorophenyl)amino]-1-piperidinyl]-2-[4-[[(3S)-3-methyl-1-piperazinyl]methyl]phenyl]-
- CBNumber
- CB02627933
- Molecular Formula
- C25H33FN4O
- Formula Weight
- 424.55
- MOL File
- 923565-21-3.mol
GSK962040 Property
- Melting point:
- 144℃
- Boiling point:
- 610.0±55.0 °C(Predicted)
- Density
- 1.175±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 9.21±0.40(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-2312
- Product name
- Camicinal
- Purity
- 95.82%
- Packaging
- 10mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- API0013933
- Product name
- GSK-962040
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $660
- Updated
- 2021/12/16
- Product number
- CS-2312
- Product name
- Camicinal
- Purity
- 95.82%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- B1149
- Product name
- GSK962040
- Packaging
- 5mg
- Price
- $512
- Updated
- 2021/12/16
- Product number
- CS-2312
- Product name
- Camicinal
- Purity
- 95.82%
- Packaging
- 50mg
- Price
- $1800
- Updated
- 2021/12/16
GSK962040 Chemical Properties,Usage,Production
Definition
ChEBI: Camicinal is a member of acetamides.
Biological Activity
Camicinal (GSK962040) is a motilin receptor agonist with a pEC50 of 7.9.
in vivo
Camicinal (GSK962040) (5 mg free base kg 1) also produced an increase in total faecal weight over the 2-h postdose period (21.2 ± 4.5 g; P < 0.05). It induced phasic contractions, the duration of which was dose-related (48 and 173 min for 3 and 6 mg kg 1), driven by mean plasma concentrations >1.14 μmol L 1. After the effects of GSK962040 faded, migrating motor complex (MMC) activity returned.
target
pEC50: 7.9 (Motilin Receptor).
GSK962040 Preparation Products And Raw materials
Raw materials
Preparation Products
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