4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile

Product Name: 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
CAS No.: 1398507-08-8
Chemical Name: 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
Synonyms: 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile;4-[(4-amino-6-chloro-2-pyrimidinyl)amino]benzonitrile
CBNumber: CB02642828
Molecular Formula: C11H8ClN5
Formula Weight: 245.66772
MOL File: 1398507-08-8.mol

More

Less

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0157470
Product name: 4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Packaging: 250mg
Price: $287
Updated: 2021/12/16

ChemScene

Product number: CS-0157470
Product name: 4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Packaging: 100mg
Price: $144
Updated: 2021/12/16

ChemScene

Product number: CS-0157470
Product name: 4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Packaging: 1g
Price: $718
Updated: 2021/12/16

AK Scientific

Product number: X6601
Product name: 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile
Packaging: 5g
Price: $2075
Updated: 2021/12/16

Crysdot

Product number: CD11265388
Product name: 4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Purity: 95+%
Packaging: 10g
Price: $2228
Updated: 2021/12/16

More

Less

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Chemical Properties,Usage,Production

Synthesis

10132-07-7

873-74-5

1398507-08-8

Example 7: Preparation of 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile (Compound Ia) To a solution of 4-aminobenzonitrile (ABN; 7 g; 59.3 mmol) in 2-butanol (190 ml) was slowly added 2,6-dichloropyrimidin-4-amine (DCAP; 10.2 g; 62.2 mmol) at room temperature. The resulting suspension was heated to reflux (102 °C) and stirred continuously for 20 hours. Upon completion of the reaction, the suspension was cooled to 20-25 °C and stirring was continued for 1 h at this temperature. The solid product was separated by filtration, washed with 2-butanol (20 ml) and subsequently dried at 50 °C for 2 h at 10 mbar. The final product was 12.20 g of 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile hydrochloride in 73.0% yield. The purity of the product was analyzed by HPLC/MS as 99.0 area%.

References

[1] Patent: WO2013/59572, 2013, A1. Location in patent: Page/Page column 17; 18

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Suppliers

China 29 India 2 United States 2 Global 33

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

BePharm Ltd

Tel: 400-685-9117
Fax: 021-51816740
Email: market@bepharm.com
Country: China
ProdList: 15081
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9713
Advantage: 58

Nanjing Dilu Pharmaceutical Co., Ltd

Tel: 18014482516
Fax: QQ2853590738
Email: 977144864@qq.com
Country: China
ProdList: 378
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Shanghai TenSus Biotechnology Co., Ltd.

Tel: 021-50895067 18616507272
Fax: 021-50895067
Email: tensus@163.com
Country: China
ProdList: 8073
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

Zhengzhou Alpha Chemical Co. LTD

Tel: 0371-0371-53732842 13383863444
Fax: QQ：3002612166
Email: 3002612166@qq.com
Country: China
ProdList: 9996
Advantage: 58

1398507-08-8, 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrileRelated Search:

Pyrimidine

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile

4-[(4-amino-6-chloro-2-pyrimidinyl)amino]benzonitrile

1398507-08-8