ChemicalBook > CAS DataBase List > 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile

Product Name
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
CAS No.
1398507-08-8
Chemical Name
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
Synonyms
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile;4-[(4-amino-6-chloro-2-pyrimidinyl)amino]benzonitrile
CBNumber
CB02642828
Molecular Formula
C11H8ClN5
Formula Weight
245.66772
MOL File
1398507-08-8.mol
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4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Property

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0157470
Product name
4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Packaging
250mg
Price
$287
Updated
2021/12/16
ChemScene
Product number
CS-0157470
Product name
4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Packaging
100mg
Price
$144
Updated
2021/12/16
ChemScene
Product number
CS-0157470
Product name
4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Packaging
1g
Price
$718
Updated
2021/12/16
AK Scientific
Product number
X6601
Product name
4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile
Packaging
5g
Price
$2075
Updated
2021/12/16
Crysdot
Product number
CD11265388
Product name
4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile
Purity
95+%
Packaging
10g
Price
$2228
Updated
2021/12/16
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4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Chemical Properties,Usage,Production

Synthesis

10132-07-7

873-74-5

1398507-08-8

Example 7: Preparation of 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile (Compound Ia) To a solution of 4-aminobenzonitrile (ABN; 7 g; 59.3 mmol) in 2-butanol (190 ml) was slowly added 2,6-dichloropyrimidin-4-amine (DCAP; 10.2 g; 62.2 mmol) at room temperature. The resulting suspension was heated to reflux (102 °C) and stirred continuously for 20 hours. Upon completion of the reaction, the suspension was cooled to 20-25 °C and stirring was continued for 1 h at this temperature. The solid product was separated by filtration, washed with 2-butanol (20 ml) and subsequently dried at 50 °C for 2 h at 10 mbar. The final product was 12.20 g of 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile hydrochloride in 73.0% yield. The purity of the product was analyzed by HPLC/MS as 99.0 area%.

References

[1] Patent: WO2013/59572, 2013, A1. Location in patent: Page/Page column 17; 18

4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Suppliers

China 29 India 2 United States 2 Global 33
Synthonix Inc
Tel
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Fax
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Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Matrix Scientific
Tel
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Fax
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Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80

1398507-08-8, 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrileRelated Search:

Pyrimidine

  • 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
  • 4-[(4-amino-6-chloro-2-pyrimidinyl)amino]benzonitrile
  • 1398507-08-8