N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE

Product Name: N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE
CAS No.: 1072145-33-5
Chemical Name: N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE
Synonyms: ERRα antagonist 1;ERRα antagonist-1, 10 mM in DMSO;N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine;N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE;5H-Dibenzo[a,d]cyclohepten-5-amine, N-[3-(4,5-dihydro-2-thiazolyl)-2-thiazolidinylidene]-;N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine 97%
CBNumber: CB02654340
Molecular Formula: C21H19N3S2
Formula Weight: 377.53
MOL File: 1072145-33-5.mol

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N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Property

Boiling point:: 579.0±60.0 °C(Predicted)
Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.98±0.10(Predicted)
form: Solid
color: White to off-white

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0393516
Product name: N-(3-(4,5-DIHYDROTHIAZOL-2-YL)THIAZOLIDIN-2-YLIDENE)-5H-DIBENZO[A,D][7]ANNULEN-5-AMINE
Purity: 95.00%
Packaging: 5MG
Price: $499.96
Updated: 2021/12/16

Ark Pharm

Product number: P000329527
Product name: N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
Purity: 97%
Packaging: 250mg
Price: $548
Updated: 2021/12/16

Apolloscientific

Product number: OR55331
Product name: N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
Purity: 97%
Packaging: 250mg
Price: $588
Updated: 2021/12/16

AK Scientific

Product number: 1518AA
Product name: N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
Packaging: 250mg
Price: $658
Updated: 2021/12/16

SynQuest Laboratories

Product number: 7H70-1-3J
Product name: N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
Purity: 97%
Packaging: 250mg
Price: $696
Updated: 2021/12/16

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N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Chemical Properties,Usage,Production

Uses

ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1[1].

IC 50

ERRα

References

[1] Michael J. Chisamore, et al. Identification of Small Molecule Estrogen-Related

N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Suppliers

China 23 India 1 United Kingdom 1 United States 7 Global 32

Shanghai EFE Biological Technology Co., Ltd.

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Energy Chemical

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cjbscvictory

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1072145-33-5, N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINERelated Search:

N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE

N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine

N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine 97%

5H-Dibenzo[a,d]cyclohepten-5-amine, N-[3-(4,5-dihydro-2-thiazolyl)-2-thiazolidinylidene]-

ERRα antagonist 1

ERRα antagonist-1, 10 mM in DMSO

1072145-33-5