ChemicalBook > CAS DataBase List > N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE
N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE
- Product Name
- N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE
- CAS No.
- 1072145-33-5
- Chemical Name
- N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE
- Synonyms
- ERRα antagonist 1;ERRα antagonist-1, 10 mM in DMSO;N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine;N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE;5H-Dibenzo[a,d]cyclohepten-5-amine, N-[3-(4,5-dihydro-2-thiazolyl)-2-thiazolidinylidene]-;N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine 97%
- CBNumber
- CB02654340
- Molecular Formula
- C21H19N3S2
- Formula Weight
- 377.53
- MOL File
- 1072145-33-5.mol
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N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Property
- Boiling point:
- 579.0±60.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.98±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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Safety
- HS Code
- 2934999090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CHM0393516
- Product name
- N-(3-(4,5-DIHYDROTHIAZOL-2-YL)THIAZOLIDIN-2-YLIDENE)-5H-DIBENZO[A,D][7]ANNULEN-5-AMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.96
- Updated
- 2021/12/16
Ark Pharm
- Product number
- P000329527
- Product name
- N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $548
- Updated
- 2021/12/16
Apolloscientific
- Product number
- OR55331
- Product name
- N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $588
- Updated
- 2021/12/16
AK Scientific
- Product number
- 1518AA
- Product name
- N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
- Packaging
- 250mg
- Price
- $658
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 7H70-1-3J
- Product name
- N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $696
- Updated
- 2021/12/16
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N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Chemical Properties,Usage,Production
Uses
ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1[1].
IC 50
ERRα
References
[1] Michael J. Chisamore, et al. Identification of Small Molecule Estrogen-Related
N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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N-[3-(4,5-DIHYDRO-2-THIAZOLYL)-2-THIAZOLIDINYLIDENE]-5H DIBENZO[A,D] CYCLOHEPTEN-5-AMINE Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88