7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo-
- Product Name
- 7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo-
- CAS No.
- 1100318-96-4
- Chemical Name
- 7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo-
- Synonyms
- 4-Iodo-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo-
- CBNumber
- CB02654830
- Molecular Formula
- C6H4IN3
- Formula Weight
- 245.02
- MOL File
- 1100318-96-4.mol
7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo- Property
- Density
- 2.219±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 11.28±0.50(Predicted)
- Appearance
- Off-white to gray Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
H320Causes eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- I706443
- Product name
- 4-Iodo-7h-pyrrolo[2,3-d]pyrimidine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- I706443
- Product name
- 4-Iodo-7h-pyrrolo[2,3-d]pyrimidine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 1917AA
- Product name
- 4-Iodo-7H-pyrrolo[2,3-d]pyrimidine
- Packaging
- 10g
- Price
- $652
- Updated
- 2021/12/16
- Product number
- 122939
- Product name
- 4-Iodo-7H-pyrrolo[2,3-d]pyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $826
- Updated
- 2021/12/16
- Product number
- CM152339
- Product name
- 4-Iodo-7H-pyrrolo[2,3-d]pyrimidine
- Purity
- 95%+
- Packaging
- 1g
- Price
- $109
- Updated
- 2021/12/16
7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo- Chemical Properties,Usage,Production
Synthesis
3680-69-1
1100318-96-4
The general procedure for the synthesis of 4-iodo-7H-pyrrolo[2,3-d]pyrimidines from 4-chloro-7H-pyrrolo[2,3-d]pyrimidines is as follows: 4-chloro-7H-pyrrolo[2,3-d]pyrimidines were dissolved in 57 wt. % aqueous hydriodic acid. The reaction mixture was stirred at room temperature for 48 h. After completion of the reaction the insoluble solids were removed by filtration. The filtrate was diluted with cold water and the pH was adjusted with aqueous ammonia solution to 8. Subsequently, the precipitated solid product was collected by filtration, washed several times with deionized water and finally dried to obtain the target compound 4-iodo-7H-pyrrolo[2,3-d]pyrimidine.
References
[1] ACS Combinatorial Science, 2015, vol. 17, # 1, p. 5 - 10
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 21, p. 5036 - 5046
[3] Patent: KR2016/124034, 2016, A. Location in patent: Paragraph 0054; 0055
[4] Patent: WO2009/9740, 2009, A1. Location in patent: Page/Page column 62
[5] Patent: EP2570125, 2013, A1. Location in patent: Paragraph 0154
7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo- Preparation Products And Raw materials
Raw materials
Preparation Products
7H-Pyrrolo[2,3-d]pyriMidine, 4-iodo- Suppliers
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