DMA
- Product Name
- DMA
- CAS No.
- 188860-26-6
- Chemical Name
- DMA
- Synonyms
- DMA, 10 mM in DMSO;2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-;2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
- CBNumber
- CB02666620
- Molecular Formula
- C27H28N6O2
- Formula Weight
- 468.55
- MOL File
- 188860-26-6.mol
DMA Property
- Melting point:
- 220 °C
- Boiling point:
- 737.3±70.0 °C(Predicted)
- Density
- 1.292±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO : ≥ 54 mg/mL (115.25 mM);
- form
- Powder
- pka
- 10.78±0.10(Predicted)
- color
- Light brown to brown
- Appearance
- Solid Powder
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- INB0004947
- Product name
- DMA
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $457.19
- Updated
- 2021/12/16
- Product number
- CD47000060
- Product name
- DMA
- Purity
- 98+%
- Packaging
- 50mg
- Price
- $168
- Updated
- 2021/12/16
- Product number
- CD47000060
- Product name
- DMA
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $224
- Updated
- 2021/12/16
DMA Chemical Properties,Usage,Production
Description
DMA is a fluorescent dye used for staining DNA.
Uses
DMA is a fluorescent compound (λex=340 nm, λem=478 nm).
Biological Activity
DMA is a fluorescent compound (λex=340 nm, λem=478 nm).
in vitro
The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87 ) in comparison to Hoechst. In case of MCF7, the IC 50 is observed at 5.3 μM for DMA. The IC 50 determined in the case of HeLa is 3.4 μM for DMA .
target
IC50: 3.4 μM (HeLa cell), 5.3 μM (MCF7 cell)
References
[1] Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69. DOI:10.1016/j.ejmech.2010.11.046
DMA Preparation Products And Raw materials
Raw materials
Preparation Products
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