1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)-

Product Name: 1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)-
CAS No.: 878006-06-5
Chemical Name: 1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)-
Synonyms: (E)-[6]-Dehydroparadol;(E)-[6]-Dehydroparadol, 10 mM in DMSO;1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)-
CBNumber: CB02667672
Molecular Formula: C17H24O3
Formula Weight: 276.37
MOL File: 878006-06-5.mol

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1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)- Property

Boiling point:: 423.2±30.0 °C(Predicted)
Density: 1.040±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 140 mg/mL (506.57 mM)
pka: 9.76±0.31(Predicted)
form: Solid
color: Yellow to orange

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-M1954
Product name: (E)-[6]-Dehydroparadol
Packaging: 5mg
Price: $108
Updated: 2021/12/16

ChemScene

Product number: CS-M1954
Product name: (E)-[6]-Dehydroparadol
Packaging: 10mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-M1954
Product name: (E)-[6]-Dehydroparadol
Packaging: 50mg
Price: $456
Updated: 2021/12/16

ChemScene

Product number: CS-M1954
Product name: (E)-[6]-Dehydroparadol
Packaging: 100mg
Price: $576
Updated: 2021/12/16

ChemScene

Product number: CS-M1954
Product name: (E)-[6]-Dehydroparadol
Packaging: 500mg
Price: $1176
Updated: 2021/12/16

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1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)- Chemical Properties,Usage,Production

Uses

(E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells[1][2].

in vivo

(E)-[6]-Dehydroparadol (compound 19) (5 μM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos^[2].

References

[1] Chen H, et, al. Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human. Mol Nutr Food Res. 2013 May;57(5):865-76. DOI:10.1002/mnfr.201200708
[2] Zhu Y, et, al. Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators. Free Radic Biol Med. 2016 Jun;95:243-54. DOI:10.1016/j.freeradbiomed.2016.03.026

1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)- Preparation Products And Raw materials

Raw materials

Preparation Products

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878006-06-5, 1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)-Related Search:

1-Decen-3-one, 1-(4-hydroxy-3-Methoxyphenyl)-, (1E)-

(E)-[6]-Dehydroparadol

(E)-[6]-Dehydroparadol, 10 mM in DMSO

878006-06-5