ChemicalBook > CAS DataBase List > L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate

L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate

Product Name: L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate
CAS No.: 57469-82-6
Chemical Name: L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate
Synonyms: Arginine Buprofen;Ketoprofen Powder;Buprofen Arginine;Ibuprofen Arginate;Ibuprofen Impurity Y;Ibuprofen L-Arginine;Ibuprofen arginine salt;Ibuprofen Arginate >=98% (HPLC);L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate;L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate
CBNumber: CB02682143
Molecular Formula: C19H32N4O4
Formula Weight: 380.48178
MOL File: 57469-82-6.mol

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L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate Property

storage temp.: 2-8°C
form: powder
color: white to beige
Water Solubility: H2O: 20mg/mL, clear
InChIKey: GCCOJNYCFNSJII-QAULRBTNNA-N
SMILES: C([C@H](N)C(=O)O)CCNC(N)=N.C(C1C=CC(CC(C)C)=CC=1)(C)C(=O)O |&1:1,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1842
Product name: Ibuprofen Arginate
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $306
Updated: 2025/07/31

AK Scientific

Product number: 8459AB
Product name: IbuprofenL-arginine
Packaging: 100mg
Price: $347
Updated: 2021/12/16

AK Scientific

Product number: 8459AB
Product name: IbuprofenL-arginine
Packaging: 5mg
Price: $49.8
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019479
Product name: (S)-2-AMINO-5-GUANIDINOPENTANOIC ACID COMPOUND WITH 2-(4-ISOBUTYLPHENYL)PROPANOIC ACID
Purity: 95.00%
Packaging: 5G
Price: $130.2
Updated: 2021/12/16

Matrix Scientific

Product number: 100435
Product name: (S)-2-Amino-5-guanidinopentanoic acid compoundwith 2-(4-isobutylphenyl)propanoic acid (1:1)
Purity: 95+%
Packaging: 250mg
Price: $742
Updated: 2021/12/16

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L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate Chemical Properties,Usage,Production

Uses

Ibuprofen arginine is an orally active L-arginine of Ibuprofen (HY-78131). With rapid absorption and high bioavailability, Ibuprofen arginine can effectively relieve a variety of acute pain, and has little damage to gastric mucosa and is well tolerated. Ibuprofen arginine can be used in research for pain relief[1].

Biological Activity

Ibuprofen arginate is the more soluble arginate salt form of the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen. Ibuprofen arginate retains the inhibitory potency against COX-2 as ibuprofen and its sodium salt, however only ibuprofen arginate is able to augment cellular NO pathway through codelivery of the NOS substrate arginine. Ibuprofen arginate, but not the sodium salt form, is shown to reverse the inhibitory effects of the cardiotoxic hormone asymmetric dimethylarginine (ADMA) and NG-nitro-L-argininemethyl ester (L-NAME) against nitric oxide synthase (eNOS & iNOS) in cultures in vitro (Murine RAW264.7 macrophages and isolated mouse & r at aorta) and effectively prevent L-NAME-induced arterial blood pressure increase in anesthetized rats in vivo (0.5 mg/kg L-NAME; 114.8 μmol/kg ibuprofen arginate, equivalent to 20 mg/kg L-Arg via femoral artery cannulation).

References

[1] Cajaraville JP. Ibuprofen Arginate for Rapid-Onset Pain Relief in Daily Practice: A Review of Its Use in Different Pain Conditions. J Pain Res. 2021 Jan 25;14:117-126. DOI:10.2147/JPR.S280571

L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate Preparation Products And Raw materials

Raw materials

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View Lastest Price from L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate manufacturers

Hebei Mingeng Biotechnology Co., Ltd

Product: Ibuprofen arginine salt 57469-82-6
Price: US $120.00/ASSAYS
Min. Order: 10g
Purity: >99%
Supply Ability: 500kg/month
Release date: 2021-11-16

Career Henan Chemical Co

Product: L-Arginine, α-Methyl-4-(2-Methylpropyl)benzeneacetate 57469-82-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KG
Release date: 2019-07-09

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57469-82-6