ChemicalBook > CAS DataBase List > Tenovin 6 (Hydrochloride)

Tenovin 6 (Hydrochloride)

Product Name: Tenovin 6 (Hydrochloride)
CAS No.: 1011301-29-3
Chemical Name: Tenovin 6 (Hydrochloride)
Synonyms: Tenovin-6.HCl;Tenovin-6 HCl, >=98%;Tenovin 6 (Hydrochloride);Tenovin-6 Hydrochloride, 10 mM in DMSO;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide hydrochloride (1:1);acetylation,Dihydroorotate Dehydrogenase,protein-deacetylating,Tenovin 6 Hydrochloride,Autophagy,Sirtuin,DHODH,Tenovin 6,Inhibitor,degradation,Tenovin6,Tenovin6 Hydrochloride,inhibit,MDM2,MDM-2/p53,Tenovin-6
CBNumber: CB02685937
Molecular Formula: C25H35ClN4O2S
Formula Weight: 491.089
MOL File: 1011301-29-3.mol

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Tenovin 6 (Hydrochloride) Property

Melting point:: >180°C (dec.)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form: Solid
color: Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13086
Product name: Tenovin-6 (hydrochloride)
Purity: ≥95%
Packaging: 1mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 13086
Product name: Tenovin-6 (hydrochloride)
Purity: ≥95%
Packaging: 5mg
Price: $717
Updated: 2024/03/01

Cayman Chemical

Product number: 13086
Product name: Tenovin-6 (hydrochloride)
Purity: ≥95%
Packaging: 10mg
Price: $1272
Updated: 2024/03/01

Cayman Chemical

Product number: 13086
Product name: Tenovin-6 (hydrochloride)
Purity: ≥95%
Packaging: 25mg
Price: $2780
Updated: 2024/03/01

ChemScene

Product number: CS-2321
Product name: Tenovin-6(Hydrochloride)
Purity: ≥98.0%
Packaging: 100mg
Price: $490
Updated: 2021/12/16

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Tenovin 6 (Hydrochloride) Chemical Properties,Usage,Production

Uses

Tenovin-6 Hydrochloride, is a small molecule activator of p53 transcriptional activity. It acts as a potent SIRT1 and SIRT2 inhibitor as well.

in vivo

Tenovin-6 Hydrochloride (50 mg/kg, i.p.) inhibits the growth of tumor in mice^[1].

IC 50

SIRT2: 10 μM (IC₅₀); SIRT1: 21 μM (IC₅₀); SIRT3: 67 μM (IC₅₀); HDAC8; MDM-2/p53

Tenovin 6 (Hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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1011301-29-3, Tenovin 6 (Hydrochloride)Related Search:

Tenovin 6 (Hydrochloride)

N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide hydrochloride (1:1)

Tenovin-6 HCl, >=98%

Tenovin-6.HCl

acetylation,Dihydroorotate Dehydrogenase,protein-deacetylating,Tenovin 6 Hydrochloride,Autophagy,Sirtuin,DHODH,Tenovin 6,Inhibitor,degradation,Tenovin6,Tenovin6 Hydrochloride,inhibit,MDM2,MDM-2/p53,Tenovin-6

Tenovin-6 Hydrochloride, 10 mM in DMSO

1011301-29-3

C25H34N4O2SHCl