ChemicalBook > CAS DataBase List > NS 3623

NS 3623

Product Name
NS 3623
CAS No.
343630-41-1
Chemical Name
NS 3623
Synonyms
NS 3623;1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea;1-(4-Bromo-2-(1H-tetrazol-5-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea;Urea, N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-N'-[3-(trifluoromethyl)phenyl]-;channels,NS 3623,midmyocardial,cardiomyocytes,current,ion,NS3623,Potassium Channel,canine,Potassium,KcsA,Inhibitor,inhibit,cells,Antiarrhythmic,effect,NS-3623
CBNumber
CB02694337
Molecular Formula
C15H10BrF3N6O
Formula Weight
427.18
MOL File
343630-41-1.mol
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NS 3623 Property

Density 
1.759±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in DMSO
form 
Powder
pka
3.95±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2843
Product name
NS3623
Purity
≥98% (HPLC)
Packaging
5MG
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2843
Product name
NS3623
Purity
≥98% (HPLC)
Packaging
25MG
Price
$476
Updated
2024/03/01
Tocris
Product number
4462
Product name
NS3623
Purity
≥99%(HPLC)
Packaging
10
Price
$233
Updated
2021/12/16
Tocris
Product number
4462
Product name
NS3623
Purity
≥99%(HPLC)
Packaging
50
Price
$980
Updated
2021/12/16
TRC
Product number
N900250
Product name
NS3623
Packaging
10mg
Price
$160
Updated
2021/12/16
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NS 3623 Chemical Properties,Usage,Production

Uses

NS 3623 selectively activates the human ether-a-go-go related gene (hERG) potassium channel which mediates the repolarizing cardiac current IKr. NS 3623 an IKr agonist, cause QT interval prolongation, increasing the risk of dangerous ventricular fibrillations, eventually leading to sudden cardiac death.

storage

Store at +4°C

NS 3623 Preparation Products And Raw materials

Raw materials

Preparation Products

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NS 3623 Suppliers

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343630-41-1, NS 3623Related Search:


  • NS 3623
  • 1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
  • N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea
  • 1-(4-Bromo-2-(1H-tetrazol-5-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
  • channels,NS 3623,midmyocardial,cardiomyocytes,current,ion,NS3623,Potassium Channel,canine,Potassium,KcsA,Inhibitor,inhibit,cells,Antiarrhythmic,effect,NS-3623
  • Urea, N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-N'-[3-(trifluoromethyl)phenyl]-
  • 343630-41-1
  • C15H10BrF3N6O
  • Agonist, Pharmaceuticals, Intermediates & Fine Chemicals